Shape andchemicalcompatibility(R groups).Explain whythe activesite isspecific to itssubstrate.Cell shrinks(crenation).Predict whathappens to ananimal cellplaced in ahypertonicsolution.Diffusion = solutemovement;Osmosis = watermovement;Facilitated =protein-assisted.Comparediffusion,osmosis, andfacilitateddiffusion.Adds closelypackednegativecharges →instability →energy release.Explain whyphosphorylationcauses a largefree energychangeChargedparticlescannot crosshydrophobiccore.Why do ionsrequiretransportproteins tocrossmembranes?High ATPdemand(muscle oractivetransport cell).A cell containsmanymitochondria—predict itsenergy demandsand role.Microtubules =transport/spindle;Actin = movement;Intermediate =structural support.Comparemicrotubules, actinfilaments, andintermediatefilamentsstructurally andfunctionally.Membranepotentialcollapses;swelling mayoccur.If the Na⁺/K⁺pump stops,predict effectson membranepotential.Prokaryotes lacknucleus/organelles;eukaryotescompartmentalized.Compareprokaryoticandeukaryotic cellorganization.Enzymesloweractivationenergy only.Explain whyenzymes donot changeΔG of areaction.Facilitatedrequiresprotein;simple doesnot.Explain howfacilitateddiffusion differsfrom simplediffusion.Hydrophobiceffect drivestails inward,headsoutward.Explain why thephospholipidbilayer formsspontaneouslyin water.Alters R-groupcharges;disruptsactive site.Why doesenzymeactivitydecrease atextreme pH?Proteins notmodified orproperlysorted.If the Golgiapparatus isnonfunctional,predict whathappens tosecreted proteins.No; lackschloroplasts.Predictwhetherphotosynthesisoccurs in aroot cell.Bondsstrained;unstableintermediatestate.Explain whythe transitionstate is highenergy.Denaturation;loss offunction.Predict enzymeactivity attemperaturesfar aboveoptimum.Cellrecognition,signaling,adhesion.Explain therole ofcarbohydratechains onglycoproteins.Plants: wall,chloroplasts,vacuole;Animals: nowall, lysosomescommon.Compare plantand animalcells in termsof structureand function.Reaction isexergonic butrequires enzymeto overcomeactivationbarrier.Interpret areaction graphshowing highactivationenergy andnegative ΔG.ATP hydrolysisreleasesenergy to driveendergonicreactions.Explain howATP drivescoupledreactions.Autodigestionof cell.Predict whathappens iflysosomesruptureinside a cell.Channelsform pores;carrierschangeshape.Explain thedifferencebetweenchannel andcarrier proteins.Passive = noATP, downgradient; Active= ATP, againstgradient.Compare passivevs activetransport in termsof energy anddirection ofmovement.Shape andchemicalcompatibility(R groups).Explain whythe activesite isspecific to itssubstrate.Cell shrinks(crenation).Predict whathappens to ananimal cellplaced in ahypertonicsolution.Diffusion = solutemovement;Osmosis = watermovement;Facilitated =protein-assisted.Comparediffusion,osmosis, andfacilitateddiffusion.Adds closelypackednegativecharges →instability →energy release.Explain whyphosphorylationcauses a largefree energychangeChargedparticlescannot crosshydrophobiccore.Why do ionsrequiretransportproteins tocrossmembranes?High ATPdemand(muscle oractivetransport cell).A cell containsmanymitochondria—predict itsenergy demandsand role.Microtubules =transport/spindle;Actin = movement;Intermediate =structural support.Comparemicrotubules, actinfilaments, andintermediatefilamentsstructurally andfunctionally.Membranepotentialcollapses;swelling mayoccur.If the Na⁺/K⁺pump stops,predict effectson membranepotential.Prokaryotes lacknucleus/organelles;eukaryotescompartmentalized.Compareprokaryoticandeukaryotic cellorganization.Enzymesloweractivationenergy only.Explain whyenzymes donot changeΔG of areaction.Facilitatedrequiresprotein;simple doesnot.Explain howfacilitateddiffusion differsfrom simplediffusion.Hydrophobiceffect drivestails inward,headsoutward.Explain why thephospholipidbilayer formsspontaneouslyin water.Alters R-groupcharges;disruptsactive site.Why doesenzymeactivitydecrease atextreme pH?Proteins notmodified orproperlysorted.If the Golgiapparatus isnonfunctional,predict whathappens tosecreted proteins.No; lackschloroplasts.Predictwhetherphotosynthesisoccurs in aroot cell.Bondsstrained;unstableintermediatestate.Explain whythe transitionstate is highenergy.Denaturation;loss offunction.Predict enzymeactivity attemperaturesfar aboveoptimum.Cellrecognition,signaling,adhesion.Explain therole ofcarbohydratechains onglycoproteins.Plants: wall,chloroplasts,vacuole;Animals: nowall, lysosomescommon.Compare plantand animalcells in termsof structureand function.Reaction isexergonic butrequires enzymeto overcomeactivationbarrier.Interpret areaction graphshowing highactivationenergy andnegative ΔG.ATP hydrolysisreleasesenergy to driveendergonicreactions.Explain howATP drivescoupledreactions.Autodigestionof cell.Predict whathappens iflysosomesruptureinside a cell.Channelsform pores;carrierschangeshape.Explain thedifferencebetweenchannel andcarrier proteins.Passive = noATP, downgradient; Active= ATP, againstgradient.Compare passivevs activetransport in termsof energy anddirection ofmovement.

Exam 2 Review - Call List

(Print) Use this randomly generated list as your call list when playing the game. There is no need to say the BINGO column name. Place some kind of mark (like an X, a checkmark, a dot, tally mark, etc) on each cell as you announce it, to keep track. You can also cut out each item, place them in a bag and pull words from the bag.


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  1. Explain why the active site is specific to its substrate.
    Shape and chemical compatibility (R groups).
  2. Predict what happens to an animal cell placed in a hypertonic solution.
    Cell shrinks (crenation).
  3. Compare diffusion, osmosis, and facilitated diffusion.
    Diffusion = solute movement; Osmosis = water movement; Facilitated = protein-assisted.
  4. Explain why phosphorylation causes a large free energy change
    Adds closely packed negative charges → instability → energy release.
  5. Why do ions require transport proteins to cross membranes?
    Charged particles cannot cross hydrophobic core.
  6. A cell contains many mitochondria—predict its energy demands and role.
    High ATP demand (muscle or active transport cell).
  7. Compare microtubules, actin filaments, and intermediate filaments structurally and functionally.
    Microtubules = transport/spindle; Actin = movement; Intermediate = structural support.
  8. If the Na⁺/K⁺ pump stops, predict effects on membrane potential.
    Membrane potential collapses; swelling may occur.
  9. Compare prokaryotic and eukaryotic cell organization.
    Prokaryotes lack nucleus/organelles; eukaryotes compartmentalized.
  10. Explain why enzymes do not change ΔG of a reaction.
    Enzymes lower activation energy only.
  11. Explain how facilitated diffusion differs from simple diffusion.
    Facilitated requires protein; simple does not.
  12. Explain why the phospholipid bilayer forms spontaneously in water.
    Hydrophobic effect drives tails inward, heads outward.
  13. Why does enzyme activity decrease at extreme pH?
    Alters R-group charges; disrupts active site.
  14. If the Golgi apparatus is nonfunctional, predict what happens to secreted proteins.
    Proteins not modified or properly sorted.
  15. Predict whether photosynthesis occurs in a root cell.
    No; lacks chloroplasts.
  16. Explain why the transition state is high energy.
    Bonds strained; unstable intermediate state.
  17. Predict enzyme activity at temperatures far above optimum.
    Denaturation; loss of function.
  18. Explain the role of carbohydrate chains on glycoproteins.
    Cell recognition, signaling, adhesion.
  19. Compare plant and animal cells in terms of structure and function.
    Plants: wall, chloroplasts, vacuole; Animals: no wall, lysosomes common.
  20. Interpret a reaction graph showing high activation energy and negative ΔG.
    Reaction is exergonic but requires enzyme to overcome activation barrier.
  21. Explain how ATP drives coupled reactions.
    ATP hydrolysis releases energy to drive endergonic reactions.
  22. Predict what happens if lysosomes rupture inside a cell.
    Autodigestion of cell.
  23. Explain the difference between channel and carrier proteins.
    Channels form pores; carriers change shape.
  24. Compare passive vs active transport in terms of energy and direction of movement.
    Passive = no ATP, down gradient; Active = ATP, against gradient.