A malignantneoplasmderived fromepithelial cellsis called a:CARCINOMAA carcinoma issurrounded by densecollagenous fibroustissue produced inresponse to thetumor. What is thiscalled?DESMOPLASIABenign tumorsgenerallyresemble theirtissue of origin.What termdescribes this?WELLDIFFERENTIATEDIn TNM,what doesT primarilyrepresent?PRIMARYTUMORSIZEA malignant epithelialtumor penetratesthrough thebasement membraneinto the underlyingstroma. Whatprocess hasoccurred?INVASIONWhat featuremay separate abenign tumorfrom thesurroundingnormal tissue?ENCAPSULATIONWhat type ofgrowth patternis characteristicof many benigntumors?EXPANSILEGROWTHA tumorcontainingtissues derivedfrom more thanone germ celllayer is called a:TERATOMAWhich tumorsuppressorgene regulatesthe G1/S cell-cyclecheckpoint?RBWhich tumorsuppressor geneis commonlycalled the“guardian of thegenome”?TP53What is theactivated form ofa proto-oncogenethat promotesuncontrolledproliferation?ONCOGENEA normal geneinvolved in cellgrowth that canbecome cancer-promoting aftermutation orinappropriateactivation is called a:PROTO-ONCOGENEIn TNM,what doesMrepresent?DISTANTMETASTASISWhat describesthe degree ofdifferentiationand cytologicaggressivenessof a tumor?GRADEA benignepithelial tumorproducing finger-like or wart-likeprojections iscalled a:PAPILLOMAWhat majorfeature isabsent intypical benignneoplasms?METASTASISWhat structuremust an epithelialcarcinomabreach tobecomeinvasive?BASEMENTMEMBRANEWhat describesthe extent ofspread ofcancerthroughout thebody?STAGEA malignantneoplasmderived frommesenchymaltissue is calleda:SARCOMAA tumor is wellcircumscribed,slow growing, andremains localized.What type ofneoplasm is this?BENIGNMalignant cellsestablish asecondary tumorin the liver afteroriginating in thecolon. What is thiscalled?METASTASISWhich proto-oncogene familyencodes smallGTP-bindingproteins and isfrequently mutatedin cancer?RASIn TNM,what doesNrepresent?REGIONALLYMPH NODEINVOLVEMENTWhat processallows agrowing tumorto develop itsown bloodsupply?ANGIOGENESISA malignantneoplasmderived fromepithelial cellsis called a:CARCINOMAA carcinoma issurrounded by densecollagenous fibroustissue produced inresponse to thetumor. What is thiscalled?DESMOPLASIABenign tumorsgenerallyresemble theirtissue of origin.What termdescribes this?WELLDIFFERENTIATEDIn TNM,what doesT primarilyrepresent?PRIMARYTUMORSIZEA malignant epithelialtumor penetratesthrough thebasement membraneinto the underlyingstroma. Whatprocess hasoccurred?INVASIONWhat featuremay separate abenign tumorfrom thesurroundingnormal tissue?ENCAPSULATIONWhat type ofgrowth patternis characteristicof many benigntumors?EXPANSILEGROWTHA tumorcontainingtissues derivedfrom more thanone germ celllayer is called a:TERATOMAWhich tumorsuppressorgene regulatesthe G1/S cell-cyclecheckpoint?RBWhich tumorsuppressor geneis commonlycalled the“guardian of thegenome”?TP53What is theactivated form ofa proto-oncogenethat promotesuncontrolledproliferation?ONCOGENEA normal geneinvolved in cellgrowth that canbecome cancer-promoting aftermutation orinappropriateactivation is called a:PROTO-ONCOGENEIn TNM,what doesMrepresent?DISTANTMETASTASISWhat describesthe degree ofdifferentiationand cytologicaggressivenessof a tumor?GRADEA benignepithelial tumorproducing finger-like or wart-likeprojections iscalled a:PAPILLOMAWhat majorfeature isabsent intypical benignneoplasms?METASTASISWhat structuremust an epithelialcarcinomabreach tobecomeinvasive?BASEMENTMEMBRANEWhat describesthe extent ofspread ofcancerthroughout thebody?STAGEA malignantneoplasmderived frommesenchymaltissue is calleda:SARCOMAA tumor is wellcircumscribed,slow growing, andremains localized.What type ofneoplasm is this?BENIGNMalignant cellsestablish asecondary tumorin the liver afteroriginating in thecolon. What is thiscalled?METASTASISWhich proto-oncogene familyencodes smallGTP-bindingproteins and isfrequently mutatedin cancer?RASIn TNM,what doesNrepresent?REGIONALLYMPH NODEINVOLVEMENTWhat processallows agrowing tumorto develop itsown bloodsupply?ANGIOGENESIS

NEOPLASIA Bingo - Call List

(Print) Use this randomly generated list as your call list when playing the game. Place some kind of mark (like an X, a checkmark, a dot, tally mark, etc) on each cell as you announce it, to keep track. You can also cut out each item, place them in a bag and pull words from the bag.


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N N
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I I
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B B
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G G
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I I
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B B
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B B
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N N
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O O
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O O
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O O
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O O
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G G
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G G
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N N
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B B
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I I
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G G
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N N
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B B
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I I
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O O
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G G
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I I
  1. N-CARCINOMA
    N-A malignant neoplasm derived from epithelial cells is called a:
  2. I-DESMOPLASIA
    I-A carcinoma is surrounded by dense collagenous fibrous tissue produced in response to the tumor. What is this called?
  3. B-WELL DIFFERENTIATED
    B-Benign tumors generally resemble their tissue of origin. What term describes this?
  4. G-PRIMARY TUMOR SIZE
    G-In TNM, what does T primarily represent?
  5. I-INVASION
    I-A malignant epithelial tumor penetrates through the basement membrane into the underlying stroma. What process has occurred?
  6. B-ENCAPSULATION
    B-What feature may separate a benign tumor from the surrounding normal tissue?
  7. B-EXPANSILE GROWTH
    B-What type of growth pattern is characteristic of many benign tumors?
  8. N-TERATOMA
    N-A tumor containing tissues derived from more than one germ cell layer is called a:
  9. O-RB
    O-Which tumor suppressor gene regulates the G1/S cell-cycle checkpoint?
  10. O-TP53
    O-Which tumor suppressor gene is commonly called the “guardian of the genome”?
  11. O-ONCOGENE
    O-What is the activated form of a proto-oncogene that promotes uncontrolled proliferation?
  12. O-PROTO-ONCOGENE
    O-A normal gene involved in cell growth that can become cancer-promoting after mutation or inappropriate activation is called a:
  13. G-DISTANT METASTASIS
    G-In TNM, what does M represent?
  14. G-GRADE
    G-What describes the degree of differentiation and cytologic aggressiveness of a tumor?
  15. N-PAPILLOMA
    N-A benign epithelial tumor producing finger-like or wart-like projections is called a:
  16. B-METASTASIS
    B-What major feature is absent in typical benign neoplasms?
  17. I-BASEMENT MEMBRANE
    I-What structure must an epithelial carcinoma breach to become invasive?
  18. G-STAGE
    G-What describes the extent of spread of cancer throughout the body?
  19. N-SARCOMA
    N-A malignant neoplasm derived from mesenchymal tissue is called a:
  20. B-BENIGN
    B-A tumor is well circumscribed, slow growing, and remains localized. What type of neoplasm is this?
  21. I-METASTASIS
    I-Malignant cells establish a secondary tumor in the liver after originating in the colon. What is this called?
  22. O-RAS
    O-Which proto-oncogene family encodes small GTP-binding proteins and is frequently mutated in cancer?
  23. G-REGIONAL LYMPH NODE INVOLVEMENT
    G-In TNM, what does N represent?
  24. I-ANGIOGENESIS
    I-What process allows a growing tumor to develop its own blood supply?