What describesthe extent ofspread ofcancerthroughout thebody?STAGEIn TNM,what doesMrepresent?DISTANTMETASTASISWhat majorfeature isabsent intypical benignneoplasms?METASTASISWhat processallows agrowing tumorto develop itsown bloodsupply?ANGIOGENESISA malignantneoplasmderived fromepithelial cellsis called a:CARCINOMAA carcinoma issurrounded by densecollagenous fibroustissue produced inresponse to thetumor. What is thiscalled?DESMOPLASIAA benignepithelial tumorproducing finger-like or wart-likeprojections iscalled a:PAPILLOMAA normal geneinvolved in cellgrowth that canbecome cancer-promoting aftermutation orinappropriateactivation is called a:PROTO-ONCOGENEA tumor is wellcircumscribed,slow growing, andremains localized.What type ofneoplasm is this?BENIGNBenign tumorsgenerallyresemble theirtissue of origin.What termdescribes this?WELLDIFFERENTIATEDWhich tumorsuppressor geneis commonlycalled the“guardian of thegenome”?TP53What is theactivated form ofa proto-oncogenethat promotesuncontrolledproliferation?ONCOGENEWhat structuremust an epithelialcarcinomabreach tobecomeinvasive?BASEMENTMEMBRANEIn TNM,what doesNrepresent?REGIONALLYMPH NODEINVOLVEMENTWhat describesthe degree ofdifferentiationand cytologicaggressivenessof a tumor?GRADEIn TNM,what doesT primarilyrepresent?PRIMARYTUMORSIZEA malignantneoplasmderived frommesenchymaltissue is calleda:SARCOMAWhich tumorsuppressorgene regulatesthe G1/S cell-cyclecheckpoint?RBWhat type ofgrowth patternis characteristicof many benigntumors?EXPANSILEGROWTHWhat featuremay separate abenign tumorfrom thesurroundingnormal tissue?ENCAPSULATIONA malignant epithelialtumor penetratesthrough thebasement membraneinto the underlyingstroma. Whatprocess hasoccurred?INVASIONWhich proto-oncogene familyencodes smallGTP-bindingproteins and isfrequently mutatedin cancer?RASA tumorcontainingtissues derivedfrom more thanone germ celllayer is called a:TERATOMAMalignant cellsestablish asecondary tumorin the liver afteroriginating in thecolon. What is thiscalled?METASTASISWhat describesthe extent ofspread ofcancerthroughout thebody?STAGEIn TNM,what doesMrepresent?DISTANTMETASTASISWhat majorfeature isabsent intypical benignneoplasms?METASTASISWhat processallows agrowing tumorto develop itsown bloodsupply?ANGIOGENESISA malignantneoplasmderived fromepithelial cellsis called a:CARCINOMAA carcinoma issurrounded by densecollagenous fibroustissue produced inresponse to thetumor. What is thiscalled?DESMOPLASIAA benignepithelial tumorproducing finger-like or wart-likeprojections iscalled a:PAPILLOMAA normal geneinvolved in cellgrowth that canbecome cancer-promoting aftermutation orinappropriateactivation is called a:PROTO-ONCOGENEA tumor is wellcircumscribed,slow growing, andremains localized.What type ofneoplasm is this?BENIGNBenign tumorsgenerallyresemble theirtissue of origin.What termdescribes this?WELLDIFFERENTIATEDWhich tumorsuppressor geneis commonlycalled the“guardian of thegenome”?TP53What is theactivated form ofa proto-oncogenethat promotesuncontrolledproliferation?ONCOGENEWhat structuremust an epithelialcarcinomabreach tobecomeinvasive?BASEMENTMEMBRANEIn TNM,what doesNrepresent?REGIONALLYMPH NODEINVOLVEMENTWhat describesthe degree ofdifferentiationand cytologicaggressivenessof a tumor?GRADEIn TNM,what doesT primarilyrepresent?PRIMARYTUMORSIZEA malignantneoplasmderived frommesenchymaltissue is calleda:SARCOMAWhich tumorsuppressorgene regulatesthe G1/S cell-cyclecheckpoint?RBWhat type ofgrowth patternis characteristicof many benigntumors?EXPANSILEGROWTHWhat featuremay separate abenign tumorfrom thesurroundingnormal tissue?ENCAPSULATIONA malignant epithelialtumor penetratesthrough thebasement membraneinto the underlyingstroma. Whatprocess hasoccurred?INVASIONWhich proto-oncogene familyencodes smallGTP-bindingproteins and isfrequently mutatedin cancer?RASA tumorcontainingtissues derivedfrom more thanone germ celllayer is called a:TERATOMAMalignant cellsestablish asecondary tumorin the liver afteroriginating in thecolon. What is thiscalled?METASTASIS

NEOPLASIA Bingo - Call List

(Print) Use this randomly generated list as your call list when playing the game. Place some kind of mark (like an X, a checkmark, a dot, tally mark, etc) on each cell as you announce it, to keep track. You can also cut out each item, place them in a bag and pull words from the bag.


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G G
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G G
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B B
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I I
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N N
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I I
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N N
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O O
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B B
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B B
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O O
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O O
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I I
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G G
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G G
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G G
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N N
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O O
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B B
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B B
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I I
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O O
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I I
  1. G-STAGE
    G-What describes the extent of spread of cancer throughout the body?
  2. G-DISTANT METASTASIS
    G-In TNM, what does M represent?
  3. B-METASTASIS
    B-What major feature is absent in typical benign neoplasms?
  4. I-ANGIOGENESIS
    I-What process allows a growing tumor to develop its own blood supply?
  5. N-CARCINOMA
    N-A malignant neoplasm derived from epithelial cells is called a:
  6. I-DESMOPLASIA
    I-A carcinoma is surrounded by dense collagenous fibrous tissue produced in response to the tumor. What is this called?
  7. N-PAPILLOMA
    N-A benign epithelial tumor producing finger-like or wart-like projections is called a:
  8. O-PROTO-ONCOGENE
    O-A normal gene involved in cell growth that can become cancer-promoting after mutation or inappropriate activation is called a:
  9. B-BENIGN
    B-A tumor is well circumscribed, slow growing, and remains localized. What type of neoplasm is this?
  10. B-WELL DIFFERENTIATED
    B-Benign tumors generally resemble their tissue of origin. What term describes this?
  11. O-TP53
    O-Which tumor suppressor gene is commonly called the “guardian of the genome”?
  12. O-ONCOGENE
    O-What is the activated form of a proto-oncogene that promotes uncontrolled proliferation?
  13. I-BASEMENT MEMBRANE
    I-What structure must an epithelial carcinoma breach to become invasive?
  14. G-REGIONAL LYMPH NODE INVOLVEMENT
    G-In TNM, what does N represent?
  15. G-GRADE
    G-What describes the degree of differentiation and cytologic aggressiveness of a tumor?
  16. G-PRIMARY TUMOR SIZE
    G-In TNM, what does T primarily represent?
  17. N-SARCOMA
    N-A malignant neoplasm derived from mesenchymal tissue is called a:
  18. O-RB
    O-Which tumor suppressor gene regulates the G1/S cell-cycle checkpoint?
  19. B-EXPANSILE GROWTH
    B-What type of growth pattern is characteristic of many benign tumors?
  20. B-ENCAPSULATION
    B-What feature may separate a benign tumor from the surrounding normal tissue?
  21. I-INVASION
    I-A malignant epithelial tumor penetrates through the basement membrane into the underlying stroma. What process has occurred?
  22. O-RAS
    O-Which proto-oncogene family encodes small GTP-binding proteins and is frequently mutated in cancer?
  23. N-TERATOMA
    N-A tumor containing tissues derived from more than one germ cell layer is called a:
  24. I-METASTASIS
    I-Malignant cells establish a secondary tumor in the liver after originating in the colon. What is this called?