What featuremay separate abenign tumorfrom thesurroundingnormal tissue?ENCAPSULATIONIn TNM,what doesT primarilyrepresent?PRIMARYTUMORSIZEA tumor is wellcircumscribed,slow growing, andremains localized.What type ofneoplasm is this?BENIGNWhich proto-oncogene familyencodes smallGTP-bindingproteins and isfrequently mutatedin cancer?RASWhich tumorsuppressor geneis commonlycalled the“guardian of thegenome”?TP53A tumor is wellcircumscribed,slow growing, andremains localized.What type ofneoplasm is this?BENIGNWhich tumorsuppressorgene regulatesthe G1/S cell-cyclecheckpoint?RBBenign tumorsgenerallyresemble theirtissue of origin.What termdescribes this?WELLDIFFERENTIATEDWhat processallows agrowing tumorto develop itsown bloodsupply?ANGIOGENESISA tumor is wellcircumscribed,slow growing, andremains localized.What type ofneoplasm is this?BENIGNA malignantneoplasmderived fromepithelial cellsis called a:CARCINOMAWhat structuremust an epithelialcarcinomabreach tobecomeinvasive?BASEMENTMEMBRANEA tumorcontainingtissues derivedfrom more thanone germ celllayer is called a:TERATOMAA carcinoma issurrounded by densecollagenous fibroustissue produced inresponse to thetumor. What is thiscalled?DESMOPLASIAA malignantneoplasmderived frommesenchymaltissue is calleda:SARCOMAIn TNM,what doesNrepresent?REGIONALLYMPH NODEINVOLVEMENTMalignant cellsestablish asecondary tumorin the liver afteroriginating in thecolon. What is thiscalled?METASTASISA benignepithelial tumorproducing finger-like or wart-likeprojections iscalled a:PAPILLOMAWhat describesthe degree ofdifferentiationand cytologicaggressivenessof a tumor?GRADEWhat type ofgrowth patternis characteristicof many benigntumors?EXPANSILEGROWTHWhat describesthe extent ofspread ofcancerthroughout thebody?STAGEA tumor is wellcircumscribed,slow growing, andremains localized.What type ofneoplasm is this?BENIGNIn TNM,what doesMrepresent?DISTANTMETASTASISA normal geneinvolved in cellgrowth that canbecome cancer-promoting aftermutation orinappropriateactivation is called a:PROTO-ONCOGENEWhat is theactivated form ofa proto-oncogenethat promotesuncontrolledproliferation?ONCOGENEA tumor is wellcircumscribed,slow growing, andremains localized.What type ofneoplasm is this?BENIGNWhat majorfeature isabsent intypical benignneoplasms?METASTASISA tumor is wellcircumscribed,slow growing, andremains localized.What type ofneoplasm is this?BENIGNA malignant epithelialtumor penetratesthrough thebasement membraneinto the underlyingstroma. Whatprocess hasoccurred?INVASIONWhat featuremay separate abenign tumorfrom thesurroundingnormal tissue?ENCAPSULATIONIn TNM,what doesT primarilyrepresent?PRIMARYTUMORSIZEA tumor is wellcircumscribed,slow growing, andremains localized.What type ofneoplasm is this?BENIGNWhich proto-oncogene familyencodes smallGTP-bindingproteins and isfrequently mutatedin cancer?RASWhich tumorsuppressor geneis commonlycalled the“guardian of thegenome”?TP53A tumor is wellcircumscribed,slow growing, andremains localized.What type ofneoplasm is this?BENIGNWhich tumorsuppressorgene regulatesthe G1/S cell-cyclecheckpoint?RBBenign tumorsgenerallyresemble theirtissue of origin.What termdescribes this?WELLDIFFERENTIATEDWhat processallows agrowing tumorto develop itsown bloodsupply?ANGIOGENESISA tumor is wellcircumscribed,slow growing, andremains localized.What type ofneoplasm is this?BENIGNA malignantneoplasmderived fromepithelial cellsis called a:CARCINOMAWhat structuremust an epithelialcarcinomabreach tobecomeinvasive?BASEMENTMEMBRANEA tumorcontainingtissues derivedfrom more thanone germ celllayer is called a:TERATOMAA carcinoma issurrounded by densecollagenous fibroustissue produced inresponse to thetumor. What is thiscalled?DESMOPLASIAA malignantneoplasmderived frommesenchymaltissue is calleda:SARCOMAIn TNM,what doesNrepresent?REGIONALLYMPH NODEINVOLVEMENTMalignant cellsestablish asecondary tumorin the liver afteroriginating in thecolon. What is thiscalled?METASTASISA benignepithelial tumorproducing finger-like or wart-likeprojections iscalled a:PAPILLOMAWhat describesthe degree ofdifferentiationand cytologicaggressivenessof a tumor?GRADEWhat type ofgrowth patternis characteristicof many benigntumors?EXPANSILEGROWTHWhat describesthe extent ofspread ofcancerthroughout thebody?STAGEA tumor is wellcircumscribed,slow growing, andremains localized.What type ofneoplasm is this?BENIGNIn TNM,what doesMrepresent?DISTANTMETASTASISA normal geneinvolved in cellgrowth that canbecome cancer-promoting aftermutation orinappropriateactivation is called a:PROTO-ONCOGENEWhat is theactivated form ofa proto-oncogenethat promotesuncontrolledproliferation?ONCOGENEA tumor is wellcircumscribed,slow growing, andremains localized.What type ofneoplasm is this?BENIGNWhat majorfeature isabsent intypical benignneoplasms?METASTASISA tumor is wellcircumscribed,slow growing, andremains localized.What type ofneoplasm is this?BENIGNA malignant epithelialtumor penetratesthrough thebasement membraneinto the underlyingstroma. Whatprocess hasoccurred?INVASION

NEOPLASIA Bingo - Call List

(Print) Use this randomly generated list as your call list when playing the game. There is no need to say the BINGO column name. Place some kind of mark (like an X, a checkmark, a dot, tally mark, etc) on each cell as you announce it, to keep track. You can also cut out each item, place them in a bag and pull words from the bag.


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  1. ENCAPSULATION
    What feature may separate a benign tumor from the surrounding normal tissue?
  2. PRIMARY TUMOR SIZE
    In TNM, what does T primarily represent?
  3. BENIGN
    A tumor is well circumscribed, slow growing, and remains localized. What type of neoplasm is this?
  4. RAS
    Which proto-oncogene family encodes small GTP-binding proteins and is frequently mutated in cancer?
  5. TP53
    Which tumor suppressor gene is commonly called the “guardian of the genome”?
  6. BENIGN
    A tumor is well circumscribed, slow growing, and remains localized. What type of neoplasm is this?
  7. RB
    Which tumor suppressor gene regulates the G1/S cell-cycle checkpoint?
  8. WELL DIFFERENTIATED
    Benign tumors generally resemble their tissue of origin. What term describes this?
  9. ANGIOGENESIS
    What process allows a growing tumor to develop its own blood supply?
  10. BENIGN
    A tumor is well circumscribed, slow growing, and remains localized. What type of neoplasm is this?
  11. CARCINOMA
    A malignant neoplasm derived from epithelial cells is called a:
  12. BASEMENT MEMBRANE
    What structure must an epithelial carcinoma breach to become invasive?
  13. TERATOMA
    A tumor containing tissues derived from more than one germ cell layer is called a:
  14. DESMOPLASIA
    A carcinoma is surrounded by dense collagenous fibrous tissue produced in response to the tumor. What is this called?
  15. SARCOMA
    A malignant neoplasm derived from mesenchymal tissue is called a:
  16. REGIONAL LYMPH NODE INVOLVEMENT
    In TNM, what does N represent?
  17. METASTASIS
    Malignant cells establish a secondary tumor in the liver after originating in the colon. What is this called?
  18. PAPILLOMA
    A benign epithelial tumor producing finger-like or wart-like projections is called a:
  19. GRADE
    What describes the degree of differentiation and cytologic aggressiveness of a tumor?
  20. EXPANSILE GROWTH
    What type of growth pattern is characteristic of many benign tumors?
  21. STAGE
    What describes the extent of spread of cancer throughout the body?
  22. BENIGN
    A tumor is well circumscribed, slow growing, and remains localized. What type of neoplasm is this?
  23. DISTANT METASTASIS
    In TNM, what does M represent?
  24. PROTO-ONCOGENE
    A normal gene involved in cell growth that can become cancer-promoting after mutation or inappropriate activation is called a:
  25. ONCOGENE
    What is the activated form of a proto-oncogene that promotes uncontrolled proliferation?
  26. BENIGN
    A tumor is well circumscribed, slow growing, and remains localized. What type of neoplasm is this?
  27. METASTASIS
    What major feature is absent in typical benign neoplasms?
  28. BENIGN
    A tumor is well circumscribed, slow growing, and remains localized. What type of neoplasm is this?
  29. INVASION
    A malignant epithelial tumor penetrates through the basement membrane into the underlying stroma. What process has occurred?