Which proto-oncogene familyencodes smallGTP-bindingproteins and isfrequently mutatedin cancer?RASA malignantneoplasmderived fromepithelial cellsis called a:CARCINOMAWhat featuremay separate abenign tumorfrom thesurroundingnormal tissue?ENCAPSULATIONA carcinoma issurrounded by densecollagenous fibroustissue produced inresponse to thetumor. What is thiscalled?DESMOPLASIAA normal geneinvolved in cellgrowth that canbecome cancer-promoting aftermutation orinappropriateactivation is called a:PROTO-ONCOGENEIn TNM,what doesT primarilyrepresent?PRIMARYTUMORSIZEBenign tumorsgenerallyresemble theirtissue of origin.What termdescribes this?WELLDIFFERENTIATEDA malignant epithelialtumor penetratesthrough thebasement membraneinto the underlyingstroma. Whatprocess hasoccurred?INVASIONA benignepithelial tumorproducing finger-like or wart-likeprojections iscalled a:PAPILLOMAA tumorcontainingtissues derivedfrom more thanone germ celllayer is called a:TERATOMAA malignantneoplasmderived frommesenchymaltissue is calleda:SARCOMAWhat structuremust an epithelialcarcinomabreach tobecomeinvasive?BASEMENTMEMBRANEA tumor is wellcircumscribed,slow growing, andremains localized.What type ofneoplasm is this?BENIGNWhat type ofgrowth patternis characteristicof many benigntumors?EXPANSILEGROWTHWhat processallows agrowing tumorto develop itsown bloodsupply?ANGIOGENESISWhich tumorsuppressorgene regulatesthe G1/S cell-cyclecheckpoint?RBA tumor is wellcircumscribed,slow growing, andremains localized.What type ofneoplasm is this?BENIGNIn TNM,what doesNrepresent?REGIONALLYMPH NODEINVOLVEMENTA tumor is wellcircumscribed,slow growing, andremains localized.What type ofneoplasm is this?BENIGNWhat describesthe degree ofdifferentiationand cytologicaggressivenessof a tumor?GRADEMalignant cellsestablish asecondary tumorin the liver afteroriginating in thecolon. What is thiscalled?METASTASISA tumor is wellcircumscribed,slow growing, andremains localized.What type ofneoplasm is this?BENIGNWhat is theactivated form ofa proto-oncogenethat promotesuncontrolledproliferation?ONCOGENEA tumor is wellcircumscribed,slow growing, andremains localized.What type ofneoplasm is this?BENIGNWhich tumorsuppressor geneis commonlycalled the“guardian of thegenome”?TP53In TNM,what doesMrepresent?DISTANTMETASTASISA tumor is wellcircumscribed,slow growing, andremains localized.What type ofneoplasm is this?BENIGNWhat describesthe extent ofspread ofcancerthroughout thebody?STAGEWhat majorfeature isabsent intypical benignneoplasms?METASTASISWhich proto-oncogene familyencodes smallGTP-bindingproteins and isfrequently mutatedin cancer?RASA malignantneoplasmderived fromepithelial cellsis called a:CARCINOMAWhat featuremay separate abenign tumorfrom thesurroundingnormal tissue?ENCAPSULATIONA carcinoma issurrounded by densecollagenous fibroustissue produced inresponse to thetumor. What is thiscalled?DESMOPLASIAA normal geneinvolved in cellgrowth that canbecome cancer-promoting aftermutation orinappropriateactivation is called a:PROTO-ONCOGENEIn TNM,what doesT primarilyrepresent?PRIMARYTUMORSIZEBenign tumorsgenerallyresemble theirtissue of origin.What termdescribes this?WELLDIFFERENTIATEDA malignant epithelialtumor penetratesthrough thebasement membraneinto the underlyingstroma. Whatprocess hasoccurred?INVASIONA benignepithelial tumorproducing finger-like or wart-likeprojections iscalled a:PAPILLOMAA tumorcontainingtissues derivedfrom more thanone germ celllayer is called a:TERATOMAA malignantneoplasmderived frommesenchymaltissue is calleda:SARCOMAWhat structuremust an epithelialcarcinomabreach tobecomeinvasive?BASEMENTMEMBRANEA tumor is wellcircumscribed,slow growing, andremains localized.What type ofneoplasm is this?BENIGNWhat type ofgrowth patternis characteristicof many benigntumors?EXPANSILEGROWTHWhat processallows agrowing tumorto develop itsown bloodsupply?ANGIOGENESISWhich tumorsuppressorgene regulatesthe G1/S cell-cyclecheckpoint?RBA tumor is wellcircumscribed,slow growing, andremains localized.What type ofneoplasm is this?BENIGNIn TNM,what doesNrepresent?REGIONALLYMPH NODEINVOLVEMENTA tumor is wellcircumscribed,slow growing, andremains localized.What type ofneoplasm is this?BENIGNWhat describesthe degree ofdifferentiationand cytologicaggressivenessof a tumor?GRADEMalignant cellsestablish asecondary tumorin the liver afteroriginating in thecolon. What is thiscalled?METASTASISA tumor is wellcircumscribed,slow growing, andremains localized.What type ofneoplasm is this?BENIGNWhat is theactivated form ofa proto-oncogenethat promotesuncontrolledproliferation?ONCOGENEA tumor is wellcircumscribed,slow growing, andremains localized.What type ofneoplasm is this?BENIGNWhich tumorsuppressor geneis commonlycalled the“guardian of thegenome”?TP53In TNM,what doesMrepresent?DISTANTMETASTASISA tumor is wellcircumscribed,slow growing, andremains localized.What type ofneoplasm is this?BENIGNWhat describesthe extent ofspread ofcancerthroughout thebody?STAGEWhat majorfeature isabsent intypical benignneoplasms?METASTASIS

NEOPLASIA Bingo - Call List

(Print) Use this randomly generated list as your call list when playing the game. There is no need to say the BINGO column name. Place some kind of mark (like an X, a checkmark, a dot, tally mark, etc) on each cell as you announce it, to keep track. You can also cut out each item, place them in a bag and pull words from the bag.


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  1. RAS
    Which proto-oncogene family encodes small GTP-binding proteins and is frequently mutated in cancer?
  2. CARCINOMA
    A malignant neoplasm derived from epithelial cells is called a:
  3. ENCAPSULATION
    What feature may separate a benign tumor from the surrounding normal tissue?
  4. DESMOPLASIA
    A carcinoma is surrounded by dense collagenous fibrous tissue produced in response to the tumor. What is this called?
  5. PROTO-ONCOGENE
    A normal gene involved in cell growth that can become cancer-promoting after mutation or inappropriate activation is called a:
  6. PRIMARY TUMOR SIZE
    In TNM, what does T primarily represent?
  7. WELL DIFFERENTIATED
    Benign tumors generally resemble their tissue of origin. What term describes this?
  8. INVASION
    A malignant epithelial tumor penetrates through the basement membrane into the underlying stroma. What process has occurred?
  9. PAPILLOMA
    A benign epithelial tumor producing finger-like or wart-like projections is called a:
  10. TERATOMA
    A tumor containing tissues derived from more than one germ cell layer is called a:
  11. SARCOMA
    A malignant neoplasm derived from mesenchymal tissue is called a:
  12. BASEMENT MEMBRANE
    What structure must an epithelial carcinoma breach to become invasive?
  13. BENIGN
    A tumor is well circumscribed, slow growing, and remains localized. What type of neoplasm is this?
  14. EXPANSILE GROWTH
    What type of growth pattern is characteristic of many benign tumors?
  15. ANGIOGENESIS
    What process allows a growing tumor to develop its own blood supply?
  16. RB
    Which tumor suppressor gene regulates the G1/S cell-cycle checkpoint?
  17. BENIGN
    A tumor is well circumscribed, slow growing, and remains localized. What type of neoplasm is this?
  18. REGIONAL LYMPH NODE INVOLVEMENT
    In TNM, what does N represent?
  19. BENIGN
    A tumor is well circumscribed, slow growing, and remains localized. What type of neoplasm is this?
  20. GRADE
    What describes the degree of differentiation and cytologic aggressiveness of a tumor?
  21. METASTASIS
    Malignant cells establish a secondary tumor in the liver after originating in the colon. What is this called?
  22. BENIGN
    A tumor is well circumscribed, slow growing, and remains localized. What type of neoplasm is this?
  23. ONCOGENE
    What is the activated form of a proto-oncogene that promotes uncontrolled proliferation?
  24. BENIGN
    A tumor is well circumscribed, slow growing, and remains localized. What type of neoplasm is this?
  25. TP53
    Which tumor suppressor gene is commonly called the “guardian of the genome”?
  26. DISTANT METASTASIS
    In TNM, what does M represent?
  27. BENIGN
    A tumor is well circumscribed, slow growing, and remains localized. What type of neoplasm is this?
  28. STAGE
    What describes the extent of spread of cancer throughout the body?
  29. METASTASIS
    What major feature is absent in typical benign neoplasms?