In TNM,what doesNrepresent?REGIONALLYMPH NODEINVOLVEMENTA malignantneoplasmderived frommesenchymaltissue is calleda:SARCOMAA tumor is wellcircumscribed,slow growing, andremains localized.What type ofneoplasm is this?BENIGNMalignant cellsestablish asecondary tumorin the liver afteroriginating in thecolon. What is thiscalled?METASTASISWhat type ofgrowth patternis characteristicof many benigntumors?EXPANSILEGROWTHIn TNM,what doesT primarilyrepresent?PRIMARYTUMORSIZEA malignant epithelialtumor penetratesthrough thebasement membraneinto the underlyingstroma. Whatprocess hasoccurred?INVASIONWhat is theactivated form ofa proto-oncogenethat promotesuncontrolledproliferation?ONCOGENEA benignepithelial tumorproducing finger-like or wart-likeprojections iscalled a:PAPILLOMAA tumorcontainingtissues derivedfrom more thanone germ celllayer is called a:TERATOMAWhat featuremay separate abenign tumorfrom thesurroundingnormal tissue?ENCAPSULATIONWhat describesthe degree ofdifferentiationand cytologicaggressivenessof a tumor?GRADEA malignantneoplasmderived fromepithelial cellsis called a:CARCINOMAWhich tumorsuppressor geneis commonlycalled the“guardian of thegenome”?TP53In TNM,what doesMrepresent?DISTANTMETASTASISWhat majorfeature isabsent intypical benignneoplasms?METASTASISA carcinoma issurrounded by densecollagenous fibroustissue produced inresponse to thetumor. What is thiscalled?DESMOPLASIABenign tumorsgenerallyresemble theirtissue of origin.What termdescribes this?WELLDIFFERENTIATEDWhich tumorsuppressorgene regulatesthe G1/S cell-cyclecheckpoint?RBWhat processallows agrowing tumorto develop itsown bloodsupply?ANGIOGENESISA normal geneinvolved in cellgrowth that canbecome cancer-promoting aftermutation orinappropriateactivation is called a:PROTO-ONCOGENEWhat describesthe extent ofspread ofcancerthroughout thebody?STAGEWhich proto-oncogene familyencodes smallGTP-bindingproteins and isfrequently mutatedin cancer?RASWhat structuremust an epithelialcarcinomabreach tobecomeinvasive?BASEMENTMEMBRANEIn TNM,what doesNrepresent?REGIONALLYMPH NODEINVOLVEMENTA malignantneoplasmderived frommesenchymaltissue is calleda:SARCOMAA tumor is wellcircumscribed,slow growing, andremains localized.What type ofneoplasm is this?BENIGNMalignant cellsestablish asecondary tumorin the liver afteroriginating in thecolon. What is thiscalled?METASTASISWhat type ofgrowth patternis characteristicof many benigntumors?EXPANSILEGROWTHIn TNM,what doesT primarilyrepresent?PRIMARYTUMORSIZEA malignant epithelialtumor penetratesthrough thebasement membraneinto the underlyingstroma. Whatprocess hasoccurred?INVASIONWhat is theactivated form ofa proto-oncogenethat promotesuncontrolledproliferation?ONCOGENEA benignepithelial tumorproducing finger-like or wart-likeprojections iscalled a:PAPILLOMAA tumorcontainingtissues derivedfrom more thanone germ celllayer is called a:TERATOMAWhat featuremay separate abenign tumorfrom thesurroundingnormal tissue?ENCAPSULATIONWhat describesthe degree ofdifferentiationand cytologicaggressivenessof a tumor?GRADEA malignantneoplasmderived fromepithelial cellsis called a:CARCINOMAWhich tumorsuppressor geneis commonlycalled the“guardian of thegenome”?TP53In TNM,what doesMrepresent?DISTANTMETASTASISWhat majorfeature isabsent intypical benignneoplasms?METASTASISA carcinoma issurrounded by densecollagenous fibroustissue produced inresponse to thetumor. What is thiscalled?DESMOPLASIABenign tumorsgenerallyresemble theirtissue of origin.What termdescribes this?WELLDIFFERENTIATEDWhich tumorsuppressorgene regulatesthe G1/S cell-cyclecheckpoint?RBWhat processallows agrowing tumorto develop itsown bloodsupply?ANGIOGENESISA normal geneinvolved in cellgrowth that canbecome cancer-promoting aftermutation orinappropriateactivation is called a:PROTO-ONCOGENEWhat describesthe extent ofspread ofcancerthroughout thebody?STAGEWhich proto-oncogene familyencodes smallGTP-bindingproteins and isfrequently mutatedin cancer?RASWhat structuremust an epithelialcarcinomabreach tobecomeinvasive?BASEMENTMEMBRANE

NEOPLASIA Bingo - Call List

(Print) Use this randomly generated list as your call list when playing the game. Place some kind of mark (like an X, a checkmark, a dot, tally mark, etc) on each cell as you announce it, to keep track. You can also cut out each item, place them in a bag and pull words from the bag.


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G G
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N N
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B B
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I I
5
B B
6
G G
7
I I
8
O O
9
N N
10
N N
11
B B
12
G G
13
N N
14
O O
15
G G
16
B B
17
I I
18
B B
19
O O
20
I I
21
O O
22
G G
23
O O
24
I I
  1. G-REGIONAL LYMPH NODE INVOLVEMENT
    G-In TNM, what does N represent?
  2. N-SARCOMA
    N-A malignant neoplasm derived from mesenchymal tissue is called a:
  3. B-BENIGN
    B-A tumor is well circumscribed, slow growing, and remains localized. What type of neoplasm is this?
  4. I-METASTASIS
    I-Malignant cells establish a secondary tumor in the liver after originating in the colon. What is this called?
  5. B-EXPANSILE GROWTH
    B-What type of growth pattern is characteristic of many benign tumors?
  6. G-PRIMARY TUMOR SIZE
    G-In TNM, what does T primarily represent?
  7. I-INVASION
    I-A malignant epithelial tumor penetrates through the basement membrane into the underlying stroma. What process has occurred?
  8. O-ONCOGENE
    O-What is the activated form of a proto-oncogene that promotes uncontrolled proliferation?
  9. N-PAPILLOMA
    N-A benign epithelial tumor producing finger-like or wart-like projections is called a:
  10. N-TERATOMA
    N-A tumor containing tissues derived from more than one germ cell layer is called a:
  11. B-ENCAPSULATION
    B-What feature may separate a benign tumor from the surrounding normal tissue?
  12. G-GRADE
    G-What describes the degree of differentiation and cytologic aggressiveness of a tumor?
  13. N-CARCINOMA
    N-A malignant neoplasm derived from epithelial cells is called a:
  14. O-TP53
    O-Which tumor suppressor gene is commonly called the “guardian of the genome”?
  15. G-DISTANT METASTASIS
    G-In TNM, what does M represent?
  16. B-METASTASIS
    B-What major feature is absent in typical benign neoplasms?
  17. I-DESMOPLASIA
    I-A carcinoma is surrounded by dense collagenous fibrous tissue produced in response to the tumor. What is this called?
  18. B-WELL DIFFERENTIATED
    B-Benign tumors generally resemble their tissue of origin. What term describes this?
  19. O-RB
    O-Which tumor suppressor gene regulates the G1/S cell-cycle checkpoint?
  20. I-ANGIOGENESIS
    I-What process allows a growing tumor to develop its own blood supply?
  21. O-PROTO-ONCOGENE
    O-A normal gene involved in cell growth that can become cancer-promoting after mutation or inappropriate activation is called a:
  22. G-STAGE
    G-What describes the extent of spread of cancer throughout the body?
  23. O-RAS
    O-Which proto-oncogene family encodes small GTP-binding proteins and is frequently mutated in cancer?
  24. I-BASEMENT MEMBRANE
    I-What structure must an epithelial carcinoma breach to become invasive?