(Print) Use this randomly generated list as your call list when playing the game. There is no need to say the BINGO column name. Place some kind of mark (like an X, a checkmark, a dot, tally mark, etc) on each cell as you announce it, to keep track. You can also cut out each item, place them in a bag and pull words from the bag.
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STAGE
What describes the extent of spread of cancer throughout the body?
INVASION
A malignant epithelial tumor penetrates through the basement membrane into the underlying stroma. What process has occurred?
ONCOGENE
What is the activated form of a proto-oncogene that promotes uncontrolled proliferation?
ENCAPSULATION
What feature may separate a benign tumor from the surrounding normal tissue?
ANGIOGENESIS
What process allows a growing tumor to develop its own blood supply?
WELL DIFFERENTIATED
Benign tumors generally resemble their tissue of origin. What term describes this?
GRADE
What describes the degree of differentiation and cytologic aggressiveness of a tumor?
PROTO-ONCOGENE
A normal gene involved in cell growth that can become cancer-promoting after mutation or inappropriate activation is called a:
DISTANT METASTASIS
In TNM, what does M represent?
CARCINOMA
A malignant neoplasm derived from epithelial cells is called a:
PAPILLOMA
A benign epithelial tumor producing finger-like or wart-like projections is called a:
RB
Which tumor suppressor gene regulates the G1/S cell-cycle checkpoint?
BENIGN
A tumor is well circumscribed, slow growing, and remains localized. What type of neoplasm is this?
EXPANSILE GROWTH
What type of growth pattern is characteristic of many benign tumors?
PRIMARY TUMOR SIZE
In TNM, what does T primarily represent?
TP53
Which tumor suppressor gene is commonly called the “guardian of the genome”?
BASEMENT MEMBRANE
What structure must an epithelial carcinoma breach to become invasive?
REGIONAL LYMPH NODE INVOLVEMENT
In TNM, what does N represent?
TERATOMA
A tumor containing tissues derived from more than one germ cell layer is called a:
DESMOPLASIA
A carcinoma is surrounded by dense collagenous fibrous tissue produced in response to the tumor. What is this called?
SARCOMA
A malignant neoplasm derived from mesenchymal tissue is called a:
METASTASIS
Malignant cells establish a secondary tumor in the liver after originating in the colon. What is this called?
METASTASIS
What major feature is absent in typical benign neoplasms?
RAS
Which proto-oncogene family encodes small GTP-binding proteins and is frequently mutated in cancer?
