A malignant epithelialtumor penetratesthrough thebasement membraneinto the underlyingstroma. Whatprocess hasoccurred?INVASIONIn TNM,what doesMrepresent?DISTANTMETASTASISA tumorcontainingtissues derivedfrom more thanone germ celllayer is called a:TERATOMAA normal geneinvolved in cellgrowth that canbecome cancer-promoting aftermutation orinappropriateactivation is called a:PROTO-ONCOGENEWhat describesthe extent ofspread ofcancerthroughout thebody?STAGEIn TNM,what doesNrepresent?REGIONALLYMPH NODEINVOLVEMENTWhich proto-oncogene familyencodes smallGTP-bindingproteins and isfrequently mutatedin cancer?RASA malignantneoplasmderived fromepithelial cellsis called a:CARCINOMAIn TNM,what doesT primarilyrepresent?PRIMARYTUMORSIZEWhich tumorsuppressorgene regulatesthe G1/S cell-cyclecheckpoint?RBBenign tumorsgenerallyresemble theirtissue of origin.What termdescribes this?WELLDIFFERENTIATEDWhich tumorsuppressor geneis commonlycalled the“guardian of thegenome”?TP53A malignantneoplasmderived frommesenchymaltissue is calleda:SARCOMAA benignepithelial tumorproducing finger-like or wart-likeprojections iscalled a:PAPILLOMAA tumor is wellcircumscribed,slow growing, andremains localized.What type ofneoplasm is this?BENIGNWhat is theactivated form ofa proto-oncogenethat promotesuncontrolledproliferation?ONCOGENEWhat majorfeature isabsent intypical benignneoplasms?METASTASISWhat describesthe degree ofdifferentiationand cytologicaggressivenessof a tumor?GRADEWhat featuremay separate abenign tumorfrom thesurroundingnormal tissue?ENCAPSULATIONWhat structuremust an epithelialcarcinomabreach tobecomeinvasive?BASEMENTMEMBRANEMalignant cellsestablish asecondary tumorin the liver afteroriginating in thecolon. What is thiscalled?METASTASISWhat type ofgrowth patternis characteristicof many benigntumors?EXPANSILEGROWTHWhat processallows agrowing tumorto develop itsown bloodsupply?ANGIOGENESISA carcinoma issurrounded by densecollagenous fibroustissue produced inresponse to thetumor. What is thiscalled?DESMOPLASIAA malignant epithelialtumor penetratesthrough thebasement membraneinto the underlyingstroma. Whatprocess hasoccurred?INVASIONIn TNM,what doesMrepresent?DISTANTMETASTASISA tumorcontainingtissues derivedfrom more thanone germ celllayer is called a:TERATOMAA normal geneinvolved in cellgrowth that canbecome cancer-promoting aftermutation orinappropriateactivation is called a:PROTO-ONCOGENEWhat describesthe extent ofspread ofcancerthroughout thebody?STAGEIn TNM,what doesNrepresent?REGIONALLYMPH NODEINVOLVEMENTWhich proto-oncogene familyencodes smallGTP-bindingproteins and isfrequently mutatedin cancer?RASA malignantneoplasmderived fromepithelial cellsis called a:CARCINOMAIn TNM,what doesT primarilyrepresent?PRIMARYTUMORSIZEWhich tumorsuppressorgene regulatesthe G1/S cell-cyclecheckpoint?RBBenign tumorsgenerallyresemble theirtissue of origin.What termdescribes this?WELLDIFFERENTIATEDWhich tumorsuppressor geneis commonlycalled the“guardian of thegenome”?TP53A malignantneoplasmderived frommesenchymaltissue is calleda:SARCOMAA benignepithelial tumorproducing finger-like or wart-likeprojections iscalled a:PAPILLOMAA tumor is wellcircumscribed,slow growing, andremains localized.What type ofneoplasm is this?BENIGNWhat is theactivated form ofa proto-oncogenethat promotesuncontrolledproliferation?ONCOGENEWhat majorfeature isabsent intypical benignneoplasms?METASTASISWhat describesthe degree ofdifferentiationand cytologicaggressivenessof a tumor?GRADEWhat featuremay separate abenign tumorfrom thesurroundingnormal tissue?ENCAPSULATIONWhat structuremust an epithelialcarcinomabreach tobecomeinvasive?BASEMENTMEMBRANEMalignant cellsestablish asecondary tumorin the liver afteroriginating in thecolon. What is thiscalled?METASTASISWhat type ofgrowth patternis characteristicof many benigntumors?EXPANSILEGROWTHWhat processallows agrowing tumorto develop itsown bloodsupply?ANGIOGENESISA carcinoma issurrounded by densecollagenous fibroustissue produced inresponse to thetumor. What is thiscalled?DESMOPLASIA

NEOPLASIA Bingo - Call List

(Print) Use this randomly generated list as your call list when playing the game. There is no need to say the BINGO column name. Place some kind of mark (like an X, a checkmark, a dot, tally mark, etc) on each cell as you announce it, to keep track. You can also cut out each item, place them in a bag and pull words from the bag.


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  1. INVASION
    A malignant epithelial tumor penetrates through the basement membrane into the underlying stroma. What process has occurred?
  2. DISTANT METASTASIS
    In TNM, what does M represent?
  3. TERATOMA
    A tumor containing tissues derived from more than one germ cell layer is called a:
  4. PROTO-ONCOGENE
    A normal gene involved in cell growth that can become cancer-promoting after mutation or inappropriate activation is called a:
  5. STAGE
    What describes the extent of spread of cancer throughout the body?
  6. REGIONAL LYMPH NODE INVOLVEMENT
    In TNM, what does N represent?
  7. RAS
    Which proto-oncogene family encodes small GTP-binding proteins and is frequently mutated in cancer?
  8. CARCINOMA
    A malignant neoplasm derived from epithelial cells is called a:
  9. PRIMARY TUMOR SIZE
    In TNM, what does T primarily represent?
  10. RB
    Which tumor suppressor gene regulates the G1/S cell-cycle checkpoint?
  11. WELL DIFFERENTIATED
    Benign tumors generally resemble their tissue of origin. What term describes this?
  12. TP53
    Which tumor suppressor gene is commonly called the “guardian of the genome”?
  13. SARCOMA
    A malignant neoplasm derived from mesenchymal tissue is called a:
  14. PAPILLOMA
    A benign epithelial tumor producing finger-like or wart-like projections is called a:
  15. BENIGN
    A tumor is well circumscribed, slow growing, and remains localized. What type of neoplasm is this?
  16. ONCOGENE
    What is the activated form of a proto-oncogene that promotes uncontrolled proliferation?
  17. METASTASIS
    What major feature is absent in typical benign neoplasms?
  18. GRADE
    What describes the degree of differentiation and cytologic aggressiveness of a tumor?
  19. ENCAPSULATION
    What feature may separate a benign tumor from the surrounding normal tissue?
  20. BASEMENT MEMBRANE
    What structure must an epithelial carcinoma breach to become invasive?
  21. METASTASIS
    Malignant cells establish a secondary tumor in the liver after originating in the colon. What is this called?
  22. EXPANSILE GROWTH
    What type of growth pattern is characteristic of many benign tumors?
  23. ANGIOGENESIS
    What process allows a growing tumor to develop its own blood supply?
  24. DESMOPLASIA
    A carcinoma is surrounded by dense collagenous fibrous tissue produced in response to the tumor. What is this called?