(Print) Use this randomly generated list as your call list when playing the game. Place some kind of mark (like an X, a checkmark, a dot, tally mark, etc) on each cell as you announce it, to keep track. You can also cut out each item, place them in a bag and pull words from the bag.
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O-O1: A normal gene involved in cell growth that can become cancer-promoting after mutation or inappropriate activation is called a:
O-O1
I-I2: Malignant cells establish a secondary tumor in the liver after originating in the colon. What is this called?
I-I2
G-G5: In TNM, what does M represent?
G-G5
B-B1: A tumor is well circumscribed, slow growing, and remains localized. What type of neoplasm is this?
B-B1
N-N4: A tumor containing tissues derived from more than one germ cell layer is called a:
N-N4
G-G3: In TNM, what does T primarily represent?
G-G3
N-N3: A benign epithelial tumor producing finger-like or wart-like projections is called a:
N-N3
G-G1: What describes the degree of differentiation and cytologic aggressiveness of a tumor?
G-G1
G-G2: What describes the extent of spread of cancer throughout the body?
G-G2
O-O3: Which tumor suppressor gene is commonly called the “guardian of the genome”?
O-O3
B-B2: What feature may separate a benign tumor from the surrounding normal tissue?
B-B2
B-B3: Benign tumors generally resemble their tissue of origin. What term describes this?
B-B3
B-B5: What major feature is absent in typical benign neoplasms?
B-B5
O-O5: Which tumor suppressor gene regulates the G1/S cell-cycle checkpoint?
O-O5
I-I5: What process allows a growing tumor to develop its own blood supply?
I-I5
I-I4: A carcinoma is surrounded by dense collagenous fibrous tissue produced in response to the tumor. What is this called?
I-I4
I-I3: What structure must an epithelial carcinoma breach to become invasive?
I-I3
B-B4: What type of growth pattern is characteristic of many benign tumors?
B-B4
O-O4: Which proto-oncogene family encodes small GTP-binding proteins and is frequently mutated in cancer?
O-O4
N-N1: A malignant neoplasm derived from epithelial cells is called a:
N-N1
N-N2: A malignant neoplasm derived from mesenchymal tissue is called a:
N-N2
O-O2: What is the activated form of a proto-oncogene that promotes uncontrolled proliferation?
O-O2
I-I1: A malignant epithelial tumor penetrates through the basement membrane into the underlying stroma. What process has occurred?
I-I1