LESS likely to produce systemic effects than oral or IV preparations Topical (nasal) Preparation p 623 Ibuprofen & Acetaminophen used in many non- prescription cold remedies p. 629 Over 7,000 # of annual visits due to dosage errors of cough/cold meds in children p 622 CNS depression Primary side effect of 1st generation antihistamines Acetylcysteine Mucolytic prototype, PO form used to treat Tylenol OD p. 627) Expectorants work by increasing production of and liquefying secretions for easier removal P 626 & 627 Many anti- depressants interact with this med Dextromethorphan p. 625 PSEUDOEPHEDRIN (SUDAFED) Prototype Decongestant p.621 Guaifenesin (Mucinex) Prototype expectorant Increases effects of pseudoephedrine cocaine,digoxin, MAO inhibitors, general anesthetics, thyroid preparations Box 31.1 Anesthetizes stretch receptors in resp passages, thereby decreasing cough Benzonatate (Tessalon Perles) Illicit manufacturing for amphetamines restricts use Psudoephedrine p.620 Narcotic known for antitussive effect Codeine p. 625 Should be avoided by elderly w/CV disease decongestants p. 621 & 623 p Produces vasoconstriciotn to decrease nasal congestion May cause rebound effects if used >3 days p. 623 Oxymetazoline (AFRIN) Am Academy of Ped's advise against antitussives in young due to thes adverse effects behavioral disturbance and respiratory depression p 625 Phenylephrine (Vazculep; Neo- Synephrine) available in eye and nasal preparation p 623) Benzonatate (Tessalon Perles) should swallowed, can cause mouth/throat numbness Suppress cough by acting on cough center in Medulla or stretch receptors in throat Antitussives p. 624 honey no strong evidence against use for tx of cough sx p. 620 Diphenhydramine (Benadryl) Used as an adjuvant med in anaphylaxis Dextromethorphan (Delsym) Prototype Antitussive Interacts w/ St. John's Wort & tryptophan with increase risk for serotonin syndrome dextromethorphan Free! nasal use may cause permanent loss of smell but herbal/oral preparation demonstrated ability to reduce severity/duration of cold sx Zinc p. 628 LESS likely to produce systemic effects than oral or IV preparations Topical (nasal) Preparation p 623 Ibuprofen & Acetaminophen used in many non- prescription cold remedies p. 629 Over 7,000 # of annual visits due to dosage errors of cough/cold meds in children p 622 CNS depression Primary side effect of 1st generation antihistamines Acetylcysteine Mucolytic prototype, PO form used to treat Tylenol OD p. 627) Expectorants work by increasing production of and liquefying secretions for easier removal P 626 & 627 Many anti- depressants interact with this med Dextromethorphan p. 625 PSEUDOEPHEDRIN (SUDAFED) Prototype Decongestant p.621 Guaifenesin (Mucinex) Prototype expectorant Increases effects of pseudoephedrine cocaine,digoxin, MAO inhibitors, general anesthetics, thyroid preparations Box 31.1 Anesthetizes stretch receptors in resp passages, thereby decreasing cough Benzonatate (Tessalon Perles) Illicit manufacturing for amphetamines restricts use Psudoephedrine p.620 Narcotic known for antitussive effect Codeine p. 625 Should be avoided by elderly w/CV disease decongestants p. 621 & 623 p Produces vasoconstriciotn to decrease nasal congestion May cause rebound effects if used >3 days p. 623 Oxymetazoline (AFRIN) Am Academy of Ped's advise against antitussives in young due to thes adverse effects behavioral disturbance and respiratory depression p 625 Phenylephrine (Vazculep; Neo- Synephrine) available in eye and nasal preparation p 623) Benzonatate (Tessalon Perles) should swallowed, can cause mouth/throat numbness Suppress cough by acting on cough center in Medulla or stretch receptors in throat Antitussives p. 624 honey no strong evidence against use for tx of cough sx p. 620 Diphenhydramine (Benadryl) Used as an adjuvant med in anaphylaxis Dextromethorphan (Delsym) Prototype Antitussive Interacts w/ St. John's Wort & tryptophan with increase risk for serotonin syndrome dextromethorphan Free! nasal use may cause permanent loss of smell but herbal/oral preparation demonstrated ability to reduce severity/duration of cold sx Zinc p. 628
(Print)
Topical (nasal) Preparation p 623
used in many non-prescription cold remedies p. 629
# of annual visits due to dosage errors of cough/cold meds in children
p 622
Primary side effect of 1st generation antihistamines
Mucolytic prototype, PO form used to treat Tylenol OD p. 627)
work by increasing production of and liquefying secretions for easier removal P 626 & 627
Dextromethorphan p. 625
Prototype Decongestant
p.621
Prototype expectorant
cocaine,digoxin, MAO inhibitors, general anesthetics, thyroid preparations
Box 31.1
Benzonatate
(Tessalon Perles)
Psudoephedrine
p.620
Codeine p. 625
decongestants
p. 621 & 623 p Produces vasoconstriciotn to decrease nasal congestion
Oxymetazoline
(AFRIN)
behavioral disturbance and respiratory depression p 625
available in eye and nasal preparation p 623)
should swallowed, can cause mouth/throat numbness
Antitussives p. 624
no strong evidence against use for tx of cough sx p. 620
Used as an adjuvant med in anaphylaxis
Prototype Antitussive
dextromethorphan
Free!
Zinc
p. 628
