PSEUDOEPHEDRIN (SUDAFED) Prototype Decongestant p.621 Acetylcysteine Mucolytic prototype, PO form used to treat Tylenol OD p. 627) Dextromethorphan (Delsym) Prototype Antitussive Illicit manufacturing for amphetamines restricts use Psudoephedrine p.620 Interacts w/ St. John's Wort & tryptophan with increase risk for serotonin syndrome dextromethorphan CNS depression Primary side effect of 1st generation antihistamines Increases effects of pseudoephedrine cocaine,digoxin, MAO inhibitors, general anesthetics, thyroid preparations Box 31.1 Many anti- depressants interact with this med Dextromethorphan p. 625 May cause rebound effects if used >3 days p. 623 Oxymetazoline (AFRIN) Guaifenesin (Mucinex) Prototype expectorant Benzonatate (Tessalon Perles) should swallowed, can cause mouth/throat numbness Should be avoided by elderly w/CV disease decongestants p. 621 & 623 p Produces vasoconstriciotn to decrease nasal congestion Expectorants work by increasing production of and liquefying secretions for easier removal P 626 & 627 Phenylephrine (Vazculep; Neo- Synephrine) available in eye and nasal preparation p 623) Narcotic known for antitussive effect Codeine p. 625 Over 7,000 # of annual visits due to dosage errors of cough/cold meds in children p 622 Diphenhydramine (Benadryl) Used as an adjuvant med in anaphylaxis Suppress cough by acting on cough center in Medulla or stretch receptors in throat Antitussives p. 624 Anesthetizes stretch receptors in resp passages, thereby decreasing cough Benzonatate (Tessalon Perles) Free! LESS likely to produce systemic effects than oral or IV preparations Topical (nasal) Preparation p 623 honey no strong evidence against use for tx of cough sx p. 620 Am Academy of Ped's advise against antitussives in young due to thes adverse effects behavioral disturbance and respiratory depression p 625 Ibuprofen & Acetaminophen used in many non- prescription cold remedies p. 629 nasal use may cause permanent loss of smell but herbal/oral preparation demonstrated ability to reduce severity/duration of cold sx Zinc p. 628 PSEUDOEPHEDRIN (SUDAFED) Prototype Decongestant p.621 Acetylcysteine Mucolytic prototype, PO form used to treat Tylenol OD p. 627) Dextromethorphan (Delsym) Prototype Antitussive Illicit manufacturing for amphetamines restricts use Psudoephedrine p.620 Interacts w/ St. John's Wort & tryptophan with increase risk for serotonin syndrome dextromethorphan CNS depression Primary side effect of 1st generation antihistamines Increases effects of pseudoephedrine cocaine,digoxin, MAO inhibitors, general anesthetics, thyroid preparations Box 31.1 Many anti- depressants interact with this med Dextromethorphan p. 625 May cause rebound effects if used >3 days p. 623 Oxymetazoline (AFRIN) Guaifenesin (Mucinex) Prototype expectorant Benzonatate (Tessalon Perles) should swallowed, can cause mouth/throat numbness Should be avoided by elderly w/CV disease decongestants p. 621 & 623 p Produces vasoconstriciotn to decrease nasal congestion Expectorants work by increasing production of and liquefying secretions for easier removal P 626 & 627 Phenylephrine (Vazculep; Neo- Synephrine) available in eye and nasal preparation p 623) Narcotic known for antitussive effect Codeine p. 625 Over 7,000 # of annual visits due to dosage errors of cough/cold meds in children p 622 Diphenhydramine (Benadryl) Used as an adjuvant med in anaphylaxis Suppress cough by acting on cough center in Medulla or stretch receptors in throat Antitussives p. 624 Anesthetizes stretch receptors in resp passages, thereby decreasing cough Benzonatate (Tessalon Perles) Free! LESS likely to produce systemic effects than oral or IV preparations Topical (nasal) Preparation p 623 honey no strong evidence against use for tx of cough sx p. 620 Am Academy of Ped's advise against antitussives in young due to thes adverse effects behavioral disturbance and respiratory depression p 625 Ibuprofen & Acetaminophen used in many non- prescription cold remedies p. 629 nasal use may cause permanent loss of smell but herbal/oral preparation demonstrated ability to reduce severity/duration of cold sx Zinc p. 628
(Print)
Prototype Decongestant
p.621
Mucolytic prototype, PO form used to treat Tylenol OD p. 627)
Prototype Antitussive
Psudoephedrine
p.620
dextromethorphan
Primary side effect of 1st generation antihistamines
cocaine,digoxin, MAO inhibitors, general anesthetics, thyroid preparations
Box 31.1
Dextromethorphan p. 625
Oxymetazoline
(AFRIN)
Prototype expectorant
should swallowed, can cause mouth/throat numbness
decongestants
p. 621 & 623 p Produces vasoconstriciotn to decrease nasal congestion
work by increasing production of and liquefying secretions for easier removal P 626 & 627
available in eye and nasal preparation p 623)
Codeine p. 625
# of annual visits due to dosage errors of cough/cold meds in children
p 622
Used as an adjuvant med in anaphylaxis
Antitussives p. 624
Benzonatate
(Tessalon Perles)
Free!
Topical (nasal) Preparation p 623
no strong evidence against use for tx of cough sx p. 620
behavioral disturbance and respiratory depression p 625
used in many non-prescription cold remedies p. 629
Zinc
p. 628
