PSEUDOEPHEDRIN (SUDAFED) Prototype Decongestant p.621 Narcotic known for antitussive effect Codeine p. 625 Anesthetizes stretch receptors in resp passages, thereby decreasing cough Benzonatate (Tessalon Perles) Phenylephrine (Vazculep; Neo- Synephrine) available in eye and nasal preparation p 623) Illicit manufacturing for amphetamines restricts use Psudoephedrine p.620 Many anti- depressants interact with this med Dextromethorphan p. 625 Over 7,000 # of annual visits due to dosage errors of cough/cold meds in children p 622 Am Academy of Ped's advise against antitussives in young due to thes adverse effects behavioral disturbance and respiratory depression p 625 Benzonatate (Tessalon Perles) should swallowed, can cause mouth/throat numbness Acetylcysteine Mucolytic prototype, PO form used to treat Tylenol OD p. 627) Diphenhydramine (Benadryl) Used as an adjuvant med in anaphylaxis Suppress cough by acting on cough center in Medulla or stretch receptors in throat Antitussives p. 624 LESS likely to produce systemic effects than oral or IV preparations Topical (nasal) Preparation p 623 CNS depression Primary side effect of 1st generation antihistamines Guaifenesin (Mucinex) Prototype expectorant Increases effects of pseudoephedrine cocaine,digoxin, MAO inhibitors, general anesthetics, thyroid preparations Box 31.1 Free! Should be avoided by elderly w/CV disease decongestants p. 621 & 623 p Produces vasoconstriciotn to decrease nasal congestion Interacts w/ St. John's Wort & tryptophan with increase risk for serotonin syndrome dextromethorphan Dextromethorphan (Delsym) Prototype Antitussive Expectorants work by increasing production of and liquefying secretions for easier removal P 626 & 627 May cause rebound effects if used >3 days p. 623 Oxymetazoline (AFRIN) honey no strong evidence against use for tx of cough sx p. 620 nasal use may cause permanent loss of smell but herbal/oral preparation demonstrated ability to reduce severity/duration of cold sx Zinc p. 628 Ibuprofen & Acetaminophen used in many non- prescription cold remedies p. 629 PSEUDOEPHEDRIN (SUDAFED) Prototype Decongestant p.621 Narcotic known for antitussive effect Codeine p. 625 Anesthetizes stretch receptors in resp passages, thereby decreasing cough Benzonatate (Tessalon Perles) Phenylephrine (Vazculep; Neo- Synephrine) available in eye and nasal preparation p 623) Illicit manufacturing for amphetamines restricts use Psudoephedrine p.620 Many anti- depressants interact with this med Dextromethorphan p. 625 Over 7,000 # of annual visits due to dosage errors of cough/cold meds in children p 622 Am Academy of Ped's advise against antitussives in young due to thes adverse effects behavioral disturbance and respiratory depression p 625 Benzonatate (Tessalon Perles) should swallowed, can cause mouth/throat numbness Acetylcysteine Mucolytic prototype, PO form used to treat Tylenol OD p. 627) Diphenhydramine (Benadryl) Used as an adjuvant med in anaphylaxis Suppress cough by acting on cough center in Medulla or stretch receptors in throat Antitussives p. 624 LESS likely to produce systemic effects than oral or IV preparations Topical (nasal) Preparation p 623 CNS depression Primary side effect of 1st generation antihistamines Guaifenesin (Mucinex) Prototype expectorant Increases effects of pseudoephedrine cocaine,digoxin, MAO inhibitors, general anesthetics, thyroid preparations Box 31.1 Free! Should be avoided by elderly w/CV disease decongestants p. 621 & 623 p Produces vasoconstriciotn to decrease nasal congestion Interacts w/ St. John's Wort & tryptophan with increase risk for serotonin syndrome dextromethorphan Dextromethorphan (Delsym) Prototype Antitussive Expectorants work by increasing production of and liquefying secretions for easier removal P 626 & 627 May cause rebound effects if used >3 days p. 623 Oxymetazoline (AFRIN) honey no strong evidence against use for tx of cough sx p. 620 nasal use may cause permanent loss of smell but herbal/oral preparation demonstrated ability to reduce severity/duration of cold sx Zinc p. 628 Ibuprofen & Acetaminophen used in many non- prescription cold remedies p. 629
(Print)
Prototype Decongestant
p.621
Codeine p. 625
Benzonatate
(Tessalon Perles)
available in eye and nasal preparation p 623)
Psudoephedrine
p.620
Dextromethorphan p. 625
# of annual visits due to dosage errors of cough/cold meds in children
p 622
behavioral disturbance and respiratory depression p 625
should swallowed, can cause mouth/throat numbness
Mucolytic prototype, PO form used to treat Tylenol OD p. 627)
Used as an adjuvant med in anaphylaxis
Antitussives p. 624
Topical (nasal) Preparation p 623
Primary side effect of 1st generation antihistamines
Prototype expectorant
cocaine,digoxin, MAO inhibitors, general anesthetics, thyroid preparations
Box 31.1
Free!
decongestants
p. 621 & 623 p Produces vasoconstriciotn to decrease nasal congestion
dextromethorphan
Prototype Antitussive
work by increasing production of and liquefying secretions for easier removal P 626 & 627
Oxymetazoline
(AFRIN)
no strong evidence against use for tx of cough sx p. 620
Zinc
p. 628
used in many non-prescription cold remedies p. 629
