Guaifenesin (Mucinex) Prototype expectorant honey no strong evidence against use for tx of cough sx p. 620 Suppress cough by acting on cough center in Medulla or stretch receptors in throat Antitussives p. 624 LESS likely to produce systemic effects than oral or IV preparations Topical (nasal) Preparation p 623 PSEUDOEPHEDRIN (SUDAFED) Prototype Decongestant p.621 CNS depression Primary side effect of 1st generation antihistamines Am Academy of Ped's advise against antitussives in young due to thes adverse effects behavioral disturbance and respiratory depression p 625 Interacts w/ St. John's Wort & tryptophan with increase risk for serotonin syndrome dextromethorphan nasal use may cause permanent loss of smell but herbal/oral preparation demonstrated ability to reduce severity/duration of cold sx Zinc p. 628 Benzonatate (Tessalon Perles) should swallowed, can cause mouth/throat numbness May cause rebound effects if used >3 days p. 623 Oxymetazoline (AFRIN) Dextromethorphan (Delsym) Prototype Antitussive Illicit manufacturing for amphetamines restricts use Psudoephedrine p.620 Acetylcysteine Mucolytic prototype, PO form used to treat Tylenol OD p. 627) Phenylephrine (Vazculep; Neo- Synephrine) available in eye and nasal preparation p 623) Increases effects of pseudoephedrine cocaine,digoxin, MAO inhibitors, general anesthetics, thyroid preparations Box 31.1 Should be avoided by elderly w/CV disease decongestants p. 621 & 623 p Produces vasoconstriciotn to decrease nasal congestion Ibuprofen & Acetaminophen used in many non- prescription cold remedies p. 629 Expectorants work by increasing production of and liquefying secretions for easier removal P 626 & 627 Diphenhydramine (Benadryl) Used as an adjuvant med in anaphylaxis Anesthetizes stretch receptors in resp passages, thereby decreasing cough Benzonatate (Tessalon Perles) Many anti- depressants interact with this med Dextromethorphan p. 625 Narcotic known for antitussive effect Codeine p. 625 Over 7,000 # of annual visits due to dosage errors of cough/cold meds in children p 622 Free! Guaifenesin (Mucinex) Prototype expectorant honey no strong evidence against use for tx of cough sx p. 620 Suppress cough by acting on cough center in Medulla or stretch receptors in throat Antitussives p. 624 LESS likely to produce systemic effects than oral or IV preparations Topical (nasal) Preparation p 623 PSEUDOEPHEDRIN (SUDAFED) Prototype Decongestant p.621 CNS depression Primary side effect of 1st generation antihistamines Am Academy of Ped's advise against antitussives in young due to thes adverse effects behavioral disturbance and respiratory depression p 625 Interacts w/ St. John's Wort & tryptophan with increase risk for serotonin syndrome dextromethorphan nasal use may cause permanent loss of smell but herbal/oral preparation demonstrated ability to reduce severity/duration of cold sx Zinc p. 628 Benzonatate (Tessalon Perles) should swallowed, can cause mouth/throat numbness May cause rebound effects if used >3 days p. 623 Oxymetazoline (AFRIN) Dextromethorphan (Delsym) Prototype Antitussive Illicit manufacturing for amphetamines restricts use Psudoephedrine p.620 Acetylcysteine Mucolytic prototype, PO form used to treat Tylenol OD p. 627) Phenylephrine (Vazculep; Neo- Synephrine) available in eye and nasal preparation p 623) Increases effects of pseudoephedrine cocaine,digoxin, MAO inhibitors, general anesthetics, thyroid preparations Box 31.1 Should be avoided by elderly w/CV disease decongestants p. 621 & 623 p Produces vasoconstriciotn to decrease nasal congestion Ibuprofen & Acetaminophen used in many non- prescription cold remedies p. 629 Expectorants work by increasing production of and liquefying secretions for easier removal P 626 & 627 Diphenhydramine (Benadryl) Used as an adjuvant med in anaphylaxis Anesthetizes stretch receptors in resp passages, thereby decreasing cough Benzonatate (Tessalon Perles) Many anti- depressants interact with this med Dextromethorphan p. 625 Narcotic known for antitussive effect Codeine p. 625 Over 7,000 # of annual visits due to dosage errors of cough/cold meds in children p 622 Free!
(Print)
Prototype expectorant
no strong evidence against use for tx of cough sx p. 620
Antitussives p. 624
Topical (nasal) Preparation p 623
Prototype Decongestant
p.621
Primary side effect of 1st generation antihistamines
behavioral disturbance and respiratory depression p 625
dextromethorphan
Zinc
p. 628
should swallowed, can cause mouth/throat numbness
Oxymetazoline
(AFRIN)
Prototype Antitussive
Psudoephedrine
p.620
Mucolytic prototype, PO form used to treat Tylenol OD p. 627)
available in eye and nasal preparation p 623)
cocaine,digoxin, MAO inhibitors, general anesthetics, thyroid preparations
Box 31.1
decongestants
p. 621 & 623 p Produces vasoconstriciotn to decrease nasal congestion
used in many non-prescription cold remedies p. 629
work by increasing production of and liquefying secretions for easier removal P 626 & 627
Used as an adjuvant med in anaphylaxis
Benzonatate
(Tessalon Perles)
Dextromethorphan p. 625
Codeine p. 625
# of annual visits due to dosage errors of cough/cold meds in children
p 622
Free!
