nasal use may cause permanent loss of smell but herbal/oral preparation demonstrated ability to reduce severity/duration of cold sx Zinc p. 628 Acetylcysteine Mucolytic prototype, PO form used to treat Tylenol OD p. 627) LESS likely to produce systemic effects than oral or IV preparations Topical (nasal) Preparation p 623 PSEUDOEPHEDRIN (SUDAFED) Prototype Decongestant p.621 Dextromethorphan (Delsym) Prototype Antitussive Benzonatate (Tessalon Perles) should swallowed, can cause mouth/throat numbness Ibuprofen & Acetaminophen used in many non- prescription cold remedies p. 629 Am Academy of Ped's advise against antitussives in young due to thes adverse effects behavioral disturbance and respiratory depression p 625 Guaifenesin (Mucinex) Prototype expectorant Expectorants work by increasing production of and liquefying secretions for easier removal P 626 & 627 Anesthetizes stretch receptors in resp passages, thereby decreasing cough Benzonatate (Tessalon Perles) Narcotic known for antitussive effect Codeine p. 625 honey no strong evidence against use for tx of cough sx p. 620 Increases effects of pseudoephedrine cocaine,digoxin, MAO inhibitors, general anesthetics, thyroid preparations Box 31.1 Should be avoided by elderly w/CV disease decongestants p. 621 & 623 p Produces vasoconstriciotn to decrease nasal congestion Illicit manufacturing for amphetamines restricts use Psudoephedrine p.620 Free! Diphenhydramine (Benadryl) Used as an adjuvant med in anaphylaxis CNS depression Primary side effect of 1st generation antihistamines Phenylephrine (Vazculep; Neo- Synephrine) available in eye and nasal preparation p 623) May cause rebound effects if used >3 days p. 623 Oxymetazoline (AFRIN) Many anti- depressants interact with this med Dextromethorphan p. 625 Over 7,000 # of annual visits due to dosage errors of cough/cold meds in children p 622 Suppress cough by acting on cough center in Medulla or stretch receptors in throat Antitussives p. 624 Interacts w/ St. John's Wort & tryptophan with increase risk for serotonin syndrome dextromethorphan nasal use may cause permanent loss of smell but herbal/oral preparation demonstrated ability to reduce severity/duration of cold sx Zinc p. 628 Acetylcysteine Mucolytic prototype, PO form used to treat Tylenol OD p. 627) LESS likely to produce systemic effects than oral or IV preparations Topical (nasal) Preparation p 623 PSEUDOEPHEDRIN (SUDAFED) Prototype Decongestant p.621 Dextromethorphan (Delsym) Prototype Antitussive Benzonatate (Tessalon Perles) should swallowed, can cause mouth/throat numbness Ibuprofen & Acetaminophen used in many non- prescription cold remedies p. 629 Am Academy of Ped's advise against antitussives in young due to thes adverse effects behavioral disturbance and respiratory depression p 625 Guaifenesin (Mucinex) Prototype expectorant Expectorants work by increasing production of and liquefying secretions for easier removal P 626 & 627 Anesthetizes stretch receptors in resp passages, thereby decreasing cough Benzonatate (Tessalon Perles) Narcotic known for antitussive effect Codeine p. 625 honey no strong evidence against use for tx of cough sx p. 620 Increases effects of pseudoephedrine cocaine,digoxin, MAO inhibitors, general anesthetics, thyroid preparations Box 31.1 Should be avoided by elderly w/CV disease decongestants p. 621 & 623 p Produces vasoconstriciotn to decrease nasal congestion Illicit manufacturing for amphetamines restricts use Psudoephedrine p.620 Free! Diphenhydramine (Benadryl) Used as an adjuvant med in anaphylaxis CNS depression Primary side effect of 1st generation antihistamines Phenylephrine (Vazculep; Neo- Synephrine) available in eye and nasal preparation p 623) May cause rebound effects if used >3 days p. 623 Oxymetazoline (AFRIN) Many anti- depressants interact with this med Dextromethorphan p. 625 Over 7,000 # of annual visits due to dosage errors of cough/cold meds in children p 622 Suppress cough by acting on cough center in Medulla or stretch receptors in throat Antitussives p. 624 Interacts w/ St. John's Wort & tryptophan with increase risk for serotonin syndrome dextromethorphan
(Print)
Zinc
p. 628
Mucolytic prototype, PO form used to treat Tylenol OD p. 627)
Topical (nasal) Preparation p 623
Prototype Decongestant
p.621
Prototype Antitussive
should swallowed, can cause mouth/throat numbness
used in many non-prescription cold remedies p. 629
behavioral disturbance and respiratory depression p 625
Prototype expectorant
work by increasing production of and liquefying secretions for easier removal P 626 & 627
Benzonatate
(Tessalon Perles)
Codeine p. 625
no strong evidence against use for tx of cough sx p. 620
cocaine,digoxin, MAO inhibitors, general anesthetics, thyroid preparations
Box 31.1
decongestants
p. 621 & 623 p Produces vasoconstriciotn to decrease nasal congestion
Psudoephedrine
p.620
Free!
Used as an adjuvant med in anaphylaxis
Primary side effect of 1st generation antihistamines
available in eye and nasal preparation p 623)
Oxymetazoline
(AFRIN)
Dextromethorphan p. 625
# of annual visits due to dosage errors of cough/cold meds in children
p 622
Antitussives p. 624
dextromethorphan
