Expectorants work by increasing production of and liquefying secretions for easier removal P 626 & 627 Dextromethorphan (Delsym) Prototype Antitussive Anesthetizes stretch receptors in resp passages, thereby decreasing cough Benzonatate (Tessalon Perles) May cause rebound effects if used >3 days p. 623 Oxymetazoline (AFRIN) Interacts w/ St. John's Wort & tryptophan with increase risk for serotonin syndrome dextromethorphan Increases effects of pseudoephedrine cocaine,digoxin, MAO inhibitors, general anesthetics, thyroid preparations Box 31.1 Acetylcysteine Mucolytic prototype, PO form used to treat Tylenol OD p. 627) nasal use may cause permanent loss of smell but herbal/oral preparation demonstrated ability to reduce severity/duration of cold sx Zinc p. 628 Narcotic known for antitussive effect Codeine p. 625 Am Academy of Ped's advise against antitussives in young due to thes adverse effects behavioral disturbance and respiratory depression p 625 Illicit manufacturing for amphetamines restricts use Psudoephedrine p.620 Over 7,000 # of annual visits due to dosage errors of cough/cold meds in children p 622 Ibuprofen & Acetaminophen used in many non- prescription cold remedies p. 629 Benzonatate (Tessalon Perles) should swallowed, can cause mouth/throat numbness Free! Guaifenesin (Mucinex) Prototype expectorant Suppress cough by acting on cough center in Medulla or stretch receptors in throat Antitussives p. 624 Phenylephrine (Vazculep; Neo- Synephrine) available in eye and nasal preparation p 623) Diphenhydramine (Benadryl) Used as an adjuvant med in anaphylaxis Many anti- depressants interact with this med Dextromethorphan p. 625 CNS depression Primary side effect of 1st generation antihistamines Should be avoided by elderly w/CV disease decongestants p. 621 & 623 p Produces vasoconstriciotn to decrease nasal congestion PSEUDOEPHEDRIN (SUDAFED) Prototype Decongestant p.621 honey no strong evidence against use for tx of cough sx p. 620 LESS likely to produce systemic effects than oral or IV preparations Topical (nasal) Preparation p 623 Expectorants work by increasing production of and liquefying secretions for easier removal P 626 & 627 Dextromethorphan (Delsym) Prototype Antitussive Anesthetizes stretch receptors in resp passages, thereby decreasing cough Benzonatate (Tessalon Perles) May cause rebound effects if used >3 days p. 623 Oxymetazoline (AFRIN) Interacts w/ St. John's Wort & tryptophan with increase risk for serotonin syndrome dextromethorphan Increases effects of pseudoephedrine cocaine,digoxin, MAO inhibitors, general anesthetics, thyroid preparations Box 31.1 Acetylcysteine Mucolytic prototype, PO form used to treat Tylenol OD p. 627) nasal use may cause permanent loss of smell but herbal/oral preparation demonstrated ability to reduce severity/duration of cold sx Zinc p. 628 Narcotic known for antitussive effect Codeine p. 625 Am Academy of Ped's advise against antitussives in young due to thes adverse effects behavioral disturbance and respiratory depression p 625 Illicit manufacturing for amphetamines restricts use Psudoephedrine p.620 Over 7,000 # of annual visits due to dosage errors of cough/cold meds in children p 622 Ibuprofen & Acetaminophen used in many non- prescription cold remedies p. 629 Benzonatate (Tessalon Perles) should swallowed, can cause mouth/throat numbness Free! Guaifenesin (Mucinex) Prototype expectorant Suppress cough by acting on cough center in Medulla or stretch receptors in throat Antitussives p. 624 Phenylephrine (Vazculep; Neo- Synephrine) available in eye and nasal preparation p 623) Diphenhydramine (Benadryl) Used as an adjuvant med in anaphylaxis Many anti- depressants interact with this med Dextromethorphan p. 625 CNS depression Primary side effect of 1st generation antihistamines Should be avoided by elderly w/CV disease decongestants p. 621 & 623 p Produces vasoconstriciotn to decrease nasal congestion PSEUDOEPHEDRIN (SUDAFED) Prototype Decongestant p.621 honey no strong evidence against use for tx of cough sx p. 620 LESS likely to produce systemic effects than oral or IV preparations Topical (nasal) Preparation p 623
(Print)
work by increasing production of and liquefying secretions for easier removal P 626 & 627
Prototype Antitussive
Benzonatate
(Tessalon Perles)
Oxymetazoline
(AFRIN)
dextromethorphan
cocaine,digoxin, MAO inhibitors, general anesthetics, thyroid preparations
Box 31.1
Mucolytic prototype, PO form used to treat Tylenol OD p. 627)
Zinc
p. 628
Codeine p. 625
behavioral disturbance and respiratory depression p 625
Psudoephedrine
p.620
# of annual visits due to dosage errors of cough/cold meds in children
p 622
used in many non-prescription cold remedies p. 629
should swallowed, can cause mouth/throat numbness
Free!
Prototype expectorant
Antitussives p. 624
available in eye and nasal preparation p 623)
Used as an adjuvant med in anaphylaxis
Dextromethorphan p. 625
Primary side effect of 1st generation antihistamines
decongestants
p. 621 & 623 p Produces vasoconstriciotn to decrease nasal congestion
Prototype Decongestant
p.621
no strong evidence against use for tx of cough sx p. 620
Topical (nasal) Preparation p 623
