May cause rebound effects if used >3 days p. 623 Oxymetazoline (AFRIN) Ibuprofen & Acetaminophen used in many non- prescription cold remedies p. 629 Illicit manufacturing for amphetamines restricts use Psudoephedrine p.620 Many anti- depressants interact with this med Dextromethorphan p. 625 Dextromethorphan (Delsym) Prototype Antitussive Diphenhydramine (Benadryl) Used as an adjuvant med in anaphylaxis Interacts w/ St. John's Wort & tryptophan with increase risk for serotonin syndrome dextromethorphan nasal use may cause permanent loss of smell but herbal/oral preparation demonstrated ability to reduce severity/duration of cold sx Zinc p. 628 Increases effects of pseudoephedrine cocaine,digoxin, MAO inhibitors, general anesthetics, thyroid preparations Box 31.1 Anesthetizes stretch receptors in resp passages, thereby decreasing cough Benzonatate (Tessalon Perles) Should be avoided by elderly w/CV disease decongestants p. 621 & 623 p Produces vasoconstriciotn to decrease nasal congestion Acetylcysteine Mucolytic prototype, PO form used to treat Tylenol OD p. 627) PSEUDOEPHEDRIN (SUDAFED) Prototype Decongestant p.621 Over 7,000 # of annual visits due to dosage errors of cough/cold meds in children p 622 Narcotic known for antitussive effect Codeine p. 625 Expectorants work by increasing production of and liquefying secretions for easier removal P 626 & 627 honey no strong evidence against use for tx of cough sx p. 620 CNS depression Primary side effect of 1st generation antihistamines LESS likely to produce systemic effects than oral or IV preparations Topical (nasal) Preparation p 623 Benzonatate (Tessalon Perles) should swallowed, can cause mouth/throat numbness Free! Am Academy of Ped's advise against antitussives in young due to thes adverse effects behavioral disturbance and respiratory depression p 625 Guaifenesin (Mucinex) Prototype expectorant Suppress cough by acting on cough center in Medulla or stretch receptors in throat Antitussives p. 624 Phenylephrine (Vazculep; Neo- Synephrine) available in eye and nasal preparation p 623) May cause rebound effects if used >3 days p. 623 Oxymetazoline (AFRIN) Ibuprofen & Acetaminophen used in many non- prescription cold remedies p. 629 Illicit manufacturing for amphetamines restricts use Psudoephedrine p.620 Many anti- depressants interact with this med Dextromethorphan p. 625 Dextromethorphan (Delsym) Prototype Antitussive Diphenhydramine (Benadryl) Used as an adjuvant med in anaphylaxis Interacts w/ St. John's Wort & tryptophan with increase risk for serotonin syndrome dextromethorphan nasal use may cause permanent loss of smell but herbal/oral preparation demonstrated ability to reduce severity/duration of cold sx Zinc p. 628 Increases effects of pseudoephedrine cocaine,digoxin, MAO inhibitors, general anesthetics, thyroid preparations Box 31.1 Anesthetizes stretch receptors in resp passages, thereby decreasing cough Benzonatate (Tessalon Perles) Should be avoided by elderly w/CV disease decongestants p. 621 & 623 p Produces vasoconstriciotn to decrease nasal congestion Acetylcysteine Mucolytic prototype, PO form used to treat Tylenol OD p. 627) PSEUDOEPHEDRIN (SUDAFED) Prototype Decongestant p.621 Over 7,000 # of annual visits due to dosage errors of cough/cold meds in children p 622 Narcotic known for antitussive effect Codeine p. 625 Expectorants work by increasing production of and liquefying secretions for easier removal P 626 & 627 honey no strong evidence against use for tx of cough sx p. 620 CNS depression Primary side effect of 1st generation antihistamines LESS likely to produce systemic effects than oral or IV preparations Topical (nasal) Preparation p 623 Benzonatate (Tessalon Perles) should swallowed, can cause mouth/throat numbness Free! Am Academy of Ped's advise against antitussives in young due to thes adverse effects behavioral disturbance and respiratory depression p 625 Guaifenesin (Mucinex) Prototype expectorant Suppress cough by acting on cough center in Medulla or stretch receptors in throat Antitussives p. 624 Phenylephrine (Vazculep; Neo- Synephrine) available in eye and nasal preparation p 623)
(Print)
Oxymetazoline
(AFRIN)
used in many non-prescription cold remedies p. 629
Psudoephedrine
p.620
Dextromethorphan p. 625
Prototype Antitussive
Used as an adjuvant med in anaphylaxis
dextromethorphan
Zinc
p. 628
cocaine,digoxin, MAO inhibitors, general anesthetics, thyroid preparations
Box 31.1
Benzonatate
(Tessalon Perles)
decongestants
p. 621 & 623 p Produces vasoconstriciotn to decrease nasal congestion
Mucolytic prototype, PO form used to treat Tylenol OD p. 627)
Prototype Decongestant
p.621
# of annual visits due to dosage errors of cough/cold meds in children
p 622
Codeine p. 625
work by increasing production of and liquefying secretions for easier removal P 626 & 627
no strong evidence against use for tx of cough sx p. 620
Primary side effect of 1st generation antihistamines
Topical (nasal) Preparation p 623
should swallowed, can cause mouth/throat numbness
Free!
behavioral disturbance and respiratory depression p 625
Prototype expectorant
Antitussives p. 624
available in eye and nasal preparation p 623)
