Diphenhydramine (Benadryl) Used as an adjuvant med in anaphylaxis Suppress cough by acting on cough center in Medulla or stretch receptors in throat Antitussives p. 624 Phenylephrine (Vazculep; Neo- Synephrine) available in eye and nasal preparation p 623) Free! CNS depression Primary side effect of 1st generation antihistamines Anesthetizes stretch receptors in resp passages, thereby decreasing cough Benzonatate (Tessalon Perles) Illicit manufacturing for amphetamines restricts use Psudoephedrine p.620 Many anti- depressants interact with this med Dextromethorphan p. 625 Am Academy of Ped's advise against antitussives in young due to thes adverse effects behavioral disturbance and respiratory depression p 625 LESS likely to produce systemic effects than oral or IV preparations Topical (nasal) Preparation p 623 nasal use may cause permanent loss of smell but herbal/oral preparation demonstrated ability to reduce severity/duration of cold sx Zinc p. 628 May cause rebound effects if used >3 days p. 623 Oxymetazoline (AFRIN) Dextromethorphan (Delsym) Prototype Antitussive Benzonatate (Tessalon Perles) should swallowed, can cause mouth/throat numbness Over 7,000 # of annual visits due to dosage errors of cough/cold meds in children p 622 Ibuprofen & Acetaminophen used in many non- prescription cold remedies p. 629 PSEUDOEPHEDRIN (SUDAFED) Prototype Decongestant p.621 Should be avoided by elderly w/CV disease decongestants p. 621 & 623 p Produces vasoconstriciotn to decrease nasal congestion honey no strong evidence against use for tx of cough sx p. 620 Expectorants work by increasing production of and liquefying secretions for easier removal P 626 & 627 Increases effects of pseudoephedrine cocaine,digoxin, MAO inhibitors, general anesthetics, thyroid preparations Box 31.1 Narcotic known for antitussive effect Codeine p. 625 Guaifenesin (Mucinex) Prototype expectorant Acetylcysteine Mucolytic prototype, PO form used to treat Tylenol OD p. 627) Interacts w/ St. John's Wort & tryptophan with increase risk for serotonin syndrome dextromethorphan Diphenhydramine (Benadryl) Used as an adjuvant med in anaphylaxis Suppress cough by acting on cough center in Medulla or stretch receptors in throat Antitussives p. 624 Phenylephrine (Vazculep; Neo- Synephrine) available in eye and nasal preparation p 623) Free! CNS depression Primary side effect of 1st generation antihistamines Anesthetizes stretch receptors in resp passages, thereby decreasing cough Benzonatate (Tessalon Perles) Illicit manufacturing for amphetamines restricts use Psudoephedrine p.620 Many anti- depressants interact with this med Dextromethorphan p. 625 Am Academy of Ped's advise against antitussives in young due to thes adverse effects behavioral disturbance and respiratory depression p 625 LESS likely to produce systemic effects than oral or IV preparations Topical (nasal) Preparation p 623 nasal use may cause permanent loss of smell but herbal/oral preparation demonstrated ability to reduce severity/duration of cold sx Zinc p. 628 May cause rebound effects if used >3 days p. 623 Oxymetazoline (AFRIN) Dextromethorphan (Delsym) Prototype Antitussive Benzonatate (Tessalon Perles) should swallowed, can cause mouth/throat numbness Over 7,000 # of annual visits due to dosage errors of cough/cold meds in children p 622 Ibuprofen & Acetaminophen used in many non- prescription cold remedies p. 629 PSEUDOEPHEDRIN (SUDAFED) Prototype Decongestant p.621 Should be avoided by elderly w/CV disease decongestants p. 621 & 623 p Produces vasoconstriciotn to decrease nasal congestion honey no strong evidence against use for tx of cough sx p. 620 Expectorants work by increasing production of and liquefying secretions for easier removal P 626 & 627 Increases effects of pseudoephedrine cocaine,digoxin, MAO inhibitors, general anesthetics, thyroid preparations Box 31.1 Narcotic known for antitussive effect Codeine p. 625 Guaifenesin (Mucinex) Prototype expectorant Acetylcysteine Mucolytic prototype, PO form used to treat Tylenol OD p. 627) Interacts w/ St. John's Wort & tryptophan with increase risk for serotonin syndrome dextromethorphan
(Print)
Used as an adjuvant med in anaphylaxis
Antitussives p. 624
available in eye and nasal preparation p 623)
Free!
Primary side effect of 1st generation antihistamines
Benzonatate
(Tessalon Perles)
Psudoephedrine
p.620
Dextromethorphan p. 625
behavioral disturbance and respiratory depression p 625
Topical (nasal) Preparation p 623
Zinc
p. 628
Oxymetazoline
(AFRIN)
Prototype Antitussive
should swallowed, can cause mouth/throat numbness
# of annual visits due to dosage errors of cough/cold meds in children
p 622
used in many non-prescription cold remedies p. 629
Prototype Decongestant
p.621
decongestants
p. 621 & 623 p Produces vasoconstriciotn to decrease nasal congestion
no strong evidence against use for tx of cough sx p. 620
work by increasing production of and liquefying secretions for easier removal P 626 & 627
cocaine,digoxin, MAO inhibitors, general anesthetics, thyroid preparations
Box 31.1
Codeine p. 625
Prototype expectorant
Mucolytic prototype, PO form used to treat Tylenol OD p. 627)
dextromethorphan
