PrimeBoostStrategiesVaccine approachused by RV144 trialthat involved theuse of a viralvector+recombinantproteinHIV-CORE004Name of thephase 1 trialfor theHIVconsvvaccinemRNAbasedvaccinetechnologyNew vaccineapproach that usesRNA to produce viralprotein to instigate animmune response.Method was used toproduce COVIDvaccinegp120Theglycoproteinthat wastargeted by theVAX 003 and004 trials85%Percentageof HIVtransmittedsexually69%Number of HIV+patients achievedcompletechimerism at 6months post-transplantCD8+T-cellName of cell thatwas found to havea significantdecrease after anHIV infection,response targetedin STEP trial15%Percentage ofHIV transmittednon-sexually(needles,blood, motherto child)3How manypatients dieddue to non-relapsecauses?100%percentage ofpatients hadundetectable HIVDNA in their bloodcells with completechimerismAMPTrialName of thetrial thatused VRC01bNAbSTEPThe name of theclinical trial that tookplace around thesame time as theSTEP trial andattempted to induceCD8+ T cell response(terminated now)MosaicvaccinedesignNew vaccineapproach thathopes to maximizeT-cell epitopes anduses artificiallyconstructedantigensRV144The name of theclinical trial that isnow consideredthe milestoneevent in HIVvaccine research4injections/halfyearDosagefor RV144trialPrEPThe name ofthe currentHIVpreventativedrugRelapse ofmalignancy(cancer)the primary causeof treatment failurein the AllogeneicHematopoietic CellTransplant studyARTThe name ofthe drug thatsuppressedHIV toundetectableamounts24.4monthsmedianfollow-uptime forsurvivors inthis studyHVTN702Clinical trial built onRV144, specifyingto clades in SouthAfrica andattempted toincrease efficacy ofRV144MF59AdjuvantThe adjuvantthat wasused in theHVTN702trialAPPROACHThe name of theclinical trial for theMosaic VaccineDesign that showedsome success forvectors Ad26 andMVAbNAbThe name of theapproach ofusing antibodiesthat recognizinga wide range ofHIV-1 strainsHepatitisBNeutralizingantibodies wereused to createa successfulvaccine for thisdisease:HIVconsvVaccineNew vaccineapproach thathopes to induce Tcell response.Notable trialsinclude HIV-CORE004AlumadjuvantThe adjuvantthat wasused in theRV144 trialCOVIDmRNA-basedvaccinetechnology wasused to create asuccessful vaccinefor this disease:IAVIG001Name of the phase1 trial of the mRNA-based vaccine, wasfound to activategermline to producethe correct bNAbsNeutralizingantibodiesApproach forHIV vaccine thattargeted gp120and gp160 andworked for HepB vaccinePrimeBoostStrategiesVaccine approachused by RV144 trialthat involved theuse of a viralvector+recombinantproteinHIV-CORE004Name of thephase 1 trialfor theHIVconsvvaccinemRNAbasedvaccinetechnologyNew vaccineapproach that usesRNA to produce viralprotein to instigate animmune response.Method was used toproduce COVIDvaccinegp120Theglycoproteinthat wastargeted by theVAX 003 and004 trials85%Percentageof HIVtransmittedsexually69%Number of HIV+patients achievedcompletechimerism at 6months post-transplantCD8+T-cellName of cell thatwas found to havea significantdecrease after anHIV infection,response targetedin STEP trial15%Percentage ofHIV transmittednon-sexually(needles,blood, motherto child)3How manypatients dieddue to non-relapsecauses?100%percentage ofpatients hadundetectable HIVDNA in their bloodcells with completechimerismAMPTrialName of thetrial thatused VRC01bNAbSTEPThe name of theclinical trial that tookplace around thesame time as theSTEP trial andattempted to induceCD8+ T cell response(terminated now)MosaicvaccinedesignNew vaccineapproach thathopes to maximizeT-cell epitopes anduses artificiallyconstructedantigensRV144The name of theclinical trial that isnow consideredthe milestoneevent in HIVvaccine research4injections/halfyearDosagefor RV144trialPrEPThe name ofthe currentHIVpreventativedrugRelapse ofmalignancy(cancer)the primary causeof treatment failurein the AllogeneicHematopoietic CellTransplant studyARTThe name ofthe drug thatsuppressedHIV toundetectableamounts24.4monthsmedianfollow-uptime forsurvivors inthis studyHVTN702Clinical trial built onRV144, specifyingto clades in SouthAfrica andattempted toincrease efficacy ofRV144MF59AdjuvantThe adjuvantthat wasused in theHVTN702trialAPPROACHThe name of theclinical trial for theMosaic VaccineDesign that showedsome success forvectors Ad26 andMVAbNAbThe name of theapproach ofusing antibodiesthat recognizinga wide range ofHIV-1 strainsHepatitisBNeutralizingantibodies wereused to createa successfulvaccine for thisdisease:HIVconsvVaccineNew vaccineapproach thathopes to induce Tcell response.Notable trialsinclude HIV-CORE004AlumadjuvantThe adjuvantthat wasused in theRV144 trialCOVIDmRNA-basedvaccinetechnology wasused to create asuccessful vaccinefor this disease:IAVIG001Name of the phase1 trial of the mRNA-based vaccine, wasfound to activategermline to producethe correct bNAbsNeutralizingantibodiesApproach forHIV vaccine thattargeted gp120and gp160 andworked for HepB vaccine

Journal Club - Call List

(Print) Use this randomly generated list as your call list when playing the game. There is no need to say the BINGO column name. Place some kind of mark (like an X, a checkmark, a dot, tally mark, etc) on each cell as you announce it, to keep track. You can also cut out each item, place them in a bag and pull words from the bag.


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  1. Vaccine approach used by RV144 trial that involved the use of a viral vector+recombinant protein
    Prime Boost Strategies
  2. Name of the phase 1 trial for the HIVconsv vaccine
    HIV-CORE 004
  3. New vaccine approach that uses RNA to produce viral protein to instigate an immune response. Method was used to produce COVID vaccine
    mRNA based vaccine technology
  4. The glycoprotein that was targeted by the VAX 003 and 004 trials
    gp120
  5. Percentage of HIV transmitted sexually
    85%
  6. Number of HIV+ patients achieved complete chimerism at 6 months post-transplant
    69%
  7. Name of cell that was found to have a significant decrease after an HIV infection, response targeted in STEP trial
    CD8+ T-cell
  8. Percentage of HIV transmitted non-sexually (needles, blood, mother to child)
    15%
  9. How many patients died due to non-relapse causes?
    3
  10. percentage of patients had undetectable HIV DNA in their blood cells with complete chimerism
    100%
  11. Name of the trial that used VRC01 bNAb
    AMP Trial
  12. The name of the clinical trial that took place around the same time as the STEP trial and attempted to induce CD8+ T cell response (terminated now)
    STEP
  13. New vaccine approach that hopes to maximize T-cell epitopes and uses artificially constructed antigens
    Mosaic vaccine design
  14. The name of the clinical trial that is now considered the milestone event in HIV vaccine research
    RV144
  15. Dosage for RV144 trial
    4 injections/half year
  16. The name of the current HIV preventative drug
    PrEP
  17. the primary cause of treatment failure in the Allogeneic Hematopoietic Cell Transplant study
    Relapse of malignancy (cancer)
  18. The name of the drug that suppressed HIV to undetectable amounts
    ART
  19. median follow-up time for survivors in this study
    24.4 months
  20. Clinical trial built on RV144, specifying to clades in South Africa and attempted to increase efficacy of RV144
    HVTN 702
  21. The adjuvant that was used in the HVTN702 trial
    MF59 Adjuvant
  22. The name of the clinical trial for the Mosaic Vaccine Design that showed some success for vectors Ad26 and MVA
    APPROACH
  23. The name of the approach of using antibodies that recognizing a wide range of HIV-1 strains
    bNAb
  24. Neutralizing antibodies were used to create a successful vaccine for this disease:
    Hepatitis B
  25. New vaccine approach that hopes to induce T cell response. Notable trials include HIV-CORE 004
    HIVconsv Vaccine
  26. The adjuvant that was used in the RV144 trial
    Alum adjuvant
  27. mRNA-based vaccine technology was used to create a successful vaccine for this disease:
    COVID
  28. Name of the phase 1 trial of the mRNA-based vaccine, was found to activate germline to produce the correct bNAbs
    IAVI G001
  29. Approach for HIV vaccine that targeted gp120 and gp160 and worked for Hep B vaccine
    Neutralizing antibodies