hCGStimTestcan distinguishbetween 5αreductasedeficiency, defectsin testosteronesynthesis andincomplete AIS 6metersLength ofhumanepididymisACTHStimtestUsed toscreenfor CAHUndervirilizedmalePreferred overmale pseudo-hermaphroditeby DrGPrimordialfolliclesThe structurethat formswhen anoogoniummatures.Testosterone19 carbonsteroidconvertedinto DHTY containingIntrabdominalgonadNeedsto beremovedAMHTGF-beta familymember thatcausesregressionof mullerianductAlfredJostExperimentswith rabbitsexplained roleof local T inmaledevelopmentReteovariiVestigialtubules andLeydig cells inhilarregion of ovary VirilizationLoss of femalebody contours,deepeningvoiceclitoromegalyetcSaltwastingSpecific formof classicCAH leadingto neonataldeathDHTActive formoftestosteroneIncompleteAISphenotype ispredominantlyundervirilizedmale withgreat range HOXGenesControl expressionof growth factorsthat induce thestraight wolffianduct to elongateand coil VirilizedfemalePreferred overfemalepseudo-hermaphroditeby DrGMetanephrousDevelopsintothe renalsystemTGF-betasuperfamilyAMH is amember ofthis super-family20weeksgestationAge withmaximumnumber offemale germcellsRenalsystemAnomalies inthis systemoften found inpatients withmulleriananomaliesSertolicellsCells thatnourishmake germcells intubules5alphareductaseEnzymethatconverts Tto DHTPGDCan be usedwith IVF toscreen forCAHMullerianductsNamed afterfamousembryologistthese ductsdevelop intofemale reproductivesystem PlacentaProtectsCAH fetusprior todeliveryInnermedullaryregionContainsovarianblood vessels,lymphaticvessels,and nerves.Germline stemcellsMice seemto havethese butwe may notLuteomaHyperplasticmassof luteinized cells1/3 associatedwith maternalhirsutismor virilization PrincetonDrG almamater andwhere authorof Middlesexwas on facultyThecaluteincysts10-20% inwomen withgestationaltrophoblasticdisease Para-mesonephrousDescribed byJohannesMuller in1830OogoniaThesediploid germcells developinto oocytesGermcellsA cell thatdevelopsinto areproductivecellSimplevirilizingNon-lethalform ofclassicCAH1/3Odds thatphenotypicsisters ofaffectedindividualare XYHyperpigmentationFrequentlyseem incasesof high levelsof ACTHCompleteAISfirst describedat Yale whereMorris coinedthe term“testicularfeminization” 21hydroxylaseDeficiency ismostcommoncause ofCAHACTHIncreasedproduction inpituitary ofCAH babiesClassicCAHCan haveboth salt-wasting andsimplevirilizing formsPseudogeneCommonmutationin classicCAHherniauterineinguinalesyndromeProbably thediagnosis ofthe Pope inConclaveMRKHCanpresentsimilar toAIS17hydroxylasedeficiencyrare causeof CAH with~ 100 casesreported AdrenalcrisisWhathappens toCAH babyafter delivery1/6Odds offemaleoffspring ofnormal sisterwill be 46 XYGranulosacellsA single layerof these cellsis found inprimordialfolliclesOutercortexConsists ofovarianfollicles andstroma inbetween themSomaticcellsIn the absenceof ovarian germcells theseovarian cellsfail to developWolffianductsMale ductsnamed afterfamousGermanembryologistand anatomistSRYRegion of Ychromosomethat leads tomaledevelopmentalpathwayCortisolSteroid that isproduced from11-deoxycortisolby 11hydroxylaseMeiosisProcess bywhichoogoniabecomeoocytes LeydigcellsAndrogenproducingcells intestes1-2%enzymeactivityPatients withsimple virilizingmost often havepoint mutationswith ___enzyme activity 6-7millionNumber ofoogonia at20 weeksgestationMesonephrosDescribedby CasparWolff in1759NomogramUsed tocomparebasal andstim levels of17-OHPTruehermaphroditeIndividualwith bothovarian andtesticulartissueHermaphroditusIn Greekmythologywas a childof Aphroditeand Hermes.17 hydroxyprogesteroneLab testused toevaluatefor CAHYupicEskimoHighestcarrierfrequencyof CAHDexamethasoneSteroidtreatment hatedby pregnantwomen at riskfor baby withCAHMiddlesexNovel byJeffreyEuginides11 betahydroxylaseAccountsfor 5-8%of CAHcasesCompoundheterozygoteNon-classicforms of 21Hydroxylasedeficiency areusually thisgenetic mixturehCGStimTestcan distinguishbetween 5αreductasedeficiency, defectsin testosteronesynthesis andincomplete AIS 6metersLength ofhumanepididymisACTHStimtestUsed toscreenfor CAHUndervirilizedmalePreferred overmale pseudo-hermaphroditeby DrGPrimordialfolliclesThe structurethat formswhen anoogoniummatures.Testosterone19 carbonsteroidconvertedinto DHTY containingIntrabdominalgonadNeedsto beremovedAMHTGF-beta familymember thatcausesregressionof mullerianductAlfredJostExperimentswith rabbitsexplained roleof local T inmaledevelopmentReteovariiVestigialtubules andLeydig cells inhilarregion of ovary VirilizationLoss of femalebody contours,deepeningvoiceclitoromegalyetcSaltwastingSpecific formof classicCAH leadingto neonataldeathDHTActive formoftestosteroneIncompleteAISphenotype ispredominantlyundervirilizedmale withgreat range HOXGenesControl expressionof growth factorsthat induce thestraight wolffianduct to elongateand coil VirilizedfemalePreferred overfemalepseudo-hermaphroditeby DrGMetanephrousDevelopsintothe renalsystemTGF-betasuperfamilyAMH is amember ofthis super-family20weeksgestationAge withmaximumnumber offemale germcellsRenalsystemAnomalies inthis systemoften found inpatients withmulleriananomaliesSertolicellsCells thatnourishmake germcells intubules5alphareductaseEnzymethatconverts Tto DHTPGDCan be usedwith IVF toscreen forCAHMullerianductsNamed afterfamousembryologistthese ductsdevelop intofemale reproductivesystem PlacentaProtectsCAH fetusprior todeliveryInnermedullaryregionContainsovarianblood vessels,lymphaticvessels,and nerves.Germline stemcellsMice seemto havethese butwe may notLuteomaHyperplasticmassof luteinized cells1/3 associatedwith maternalhirsutismor virilization PrincetonDrG almamater andwhere authorof Middlesexwas on facultyThecaluteincysts10-20% inwomen withgestationaltrophoblasticdisease Para-mesonephrousDescribed byJohannesMuller in1830OogoniaThesediploid germcells developinto oocytesGermcellsA cell thatdevelopsinto areproductivecellSimplevirilizingNon-lethalform ofclassicCAH1/3Odds thatphenotypicsisters ofaffectedindividualare XYHyperpigmentationFrequentlyseem incasesof high levelsof ACTHCompleteAISfirst describedat Yale whereMorris coinedthe term“testicularfeminization” 21hydroxylaseDeficiency ismostcommoncause ofCAHACTHIncreasedproduction inpituitary ofCAH babiesClassicCAHCan haveboth salt-wasting andsimplevirilizing formsPseudogeneCommonmutationin classicCAHherniauterineinguinalesyndromeProbably thediagnosis ofthe Pope inConclaveMRKHCanpresentsimilar toAIS17hydroxylasedeficiencyrare causeof CAH with~ 100 casesreported AdrenalcrisisWhathappens toCAH babyafter delivery1/6Odds offemaleoffspring ofnormal sisterwill be 46 XYGranulosacellsA single layerof these cellsis found inprimordialfolliclesOutercortexConsists ofovarianfollicles andstroma inbetween themSomaticcellsIn the absenceof ovarian germcells theseovarian cellsfail to developWolffianductsMale ductsnamed afterfamousGermanembryologistand anatomistSRYRegion of Ychromosomethat leads tomaledevelopmentalpathwayCortisolSteroid that isproduced from11-deoxycortisolby 11hydroxylaseMeiosisProcess bywhichoogoniabecomeoocytes LeydigcellsAndrogenproducingcells intestes1-2%enzymeactivityPatients withsimple virilizingmost often havepoint mutationswith ___enzyme activity 6-7millionNumber ofoogonia at20 weeksgestationMesonephrosDescribedby CasparWolff in1759NomogramUsed tocomparebasal andstim levels of17-OHPTruehermaphroditeIndividualwith bothovarian andtesticulartissueHermaphroditusIn Greekmythologywas a childof Aphroditeand Hermes.17 hydroxyprogesteroneLab testused toevaluatefor CAHYupicEskimoHighestcarrierfrequencyof CAHDexamethasoneSteroidtreatment hatedby pregnantwomen at riskfor baby withCAHMiddlesexNovel byJeffreyEuginides11 betahydroxylaseAccountsfor 5-8%of CAHcasesCompoundheterozygoteNon-classicforms of 21Hydroxylasedeficiency areusually thisgenetic mixture

REI DSD Bingo - Call List

(Print) Use this randomly generated list as your call list when playing the game. There is no need to say the BINGO column name. Place some kind of mark (like an X, a checkmark, a dot, tally mark, etc) on each cell as you announce it, to keep track. You can also cut out each item, place them in a bag and pull words from the bag.


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  1. can distinguish between 5α reductase deficiency, defects in testosterone synthesis and incomplete AIS
    hCG Stim Test
  2. Length of human epididymis
    6 meters
  3. Used to screen for CAH
    ACTH Stim test
  4. Preferred over male pseudo-hermaphrodite by DrG
    Undervirilized male
  5. The structure that forms when an oogonium matures.
    Primordial follicles
  6. 19 carbon steroid converted into DHT
    Testosterone
  7. Needs to be removed
    Y containing Intrabdominal gonad
  8. TGF-beta family member that causes regression of mullerian duct
    AMH
  9. Experiments with rabbits explained role of local T in male development
    Alfred Jost
  10. Vestigial tubules and Leydig cells in hilar region of ovary
    Rete ovarii
  11. Loss of female body contours, deepening voice clitoromegaly etc
    Virilization
  12. Specific form of classic CAH leading to neonatal death
    Salt wasting
  13. Active form of testosterone
    DHT
  14. phenotype is predominantly undervirilized male with great range
    Incomplete AIS
  15. Control expression of growth factors that induce the straight wolffian duct to elongate and coil
    HOX Genes
  16. Preferred over female pseudo-hermaphrodite by DrG
    Virilized female
  17. Develops into the renal system
    Metanephrous
  18. AMH is a member of this super- family
    TGF-beta superfamily
  19. Age with maximum number of female germ cells
    20 weeks gestation
  20. Anomalies in this system often found in patients with mullerian anomalies
    Renal system
  21. Cells that nourish make germ cells in tubules
    Sertoli cells
  22. Enzyme that converts T to DHT
    5alpha reductase
  23. Can be used with IVF to screen for CAH
    PGD
  24. Named after famous embryologist these ducts develop into female reproductive system
    Mullerian ducts
  25. Protects CAH fetus prior to delivery
    Placenta
  26. Contains ovarian blood vessels, lymphatic vessels, and nerves.
    Inner medullary region
  27. Mice seem to have these but we may not
    Germ line stem cells
  28. Hyperplastic mass of luteinized cells 1/3 associated with maternal hirsutism or virilization
    Luteoma
  29. DrG alma mater and where author of Middlesex was on faculty
    Princeton
  30. 10-20% in women with gestational trophoblastic disease
    Theca lutein cysts
  31. Described by Johannes Muller in 1830
    Para-mesonephrous
  32. These diploid germ cells develop into oocytes
    Oogonia
  33. A cell that develops into a reproductive cell
    Germ cells
  34. Non-lethal form of classic CAH
    Simple virilizing
  35. Odds that phenotypic sisters of affected individual are XY
    1/3
  36. Frequently seem in cases of high levels of ACTH
    Hyper pigmentation
  37. first described at Yale where Morris coined the term “testicular feminization”
    Complete AIS
  38. Deficiency is most common cause of CAH
    21 hydroxylase
  39. Increased production in pituitary of CAH babies
    ACTH
  40. Can have both salt-wasting and simple virilizing forms
    Classic CAH
  41. Common mutation in classic CAH
    Pseudogene
  42. Probably the diagnosis of the Pope in Conclave
    hernia uterine inguinale syndrome
  43. Can present similar to AIS
    MRKH
  44. rare cause of CAH with ~ 100 cases reported
    17 hydroxylase deficiency
  45. What happens to CAH baby after delivery
    Adrenal crisis
  46. Odds of female offspring of normal sister will be 46 XY
    1/6
  47. A single layer of these cells is found in primordial follicles
    Granulosa cells
  48. Consists of ovarian follicles and stroma in between them
    Outer cortex
  49. In the absence of ovarian germ cells these ovarian cells fail to develop
    Somatic cells
  50. Male ducts named after famous German embryologist and anatomist
    Wolffian ducts
  51. Region of Y chromosome that leads to male developmental pathway
    SRY
  52. Steroid that is produced from 11-deoxycortisol by 11 hydroxylase
    Cortisol
  53. Process by which oogonia become oocytes
    Meiosis
  54. Androgen producing cells in testes
    Leydig cells
  55. Patients with simple virilizing most often have point mutations with ___ enzyme activity
    1-2% enzyme activity
  56. Number of oogonia at 20 weeks gestation
    6-7 million
  57. Described by Caspar Wolff in 1759
    Mesonephros
  58. Used to compare basal and stim levels of 17-OHP
    Nomogram
  59. Individual with both ovarian and testicular tissue
    True hermaphrodite
  60. In Greek mythology was a child of Aphrodite and Hermes.
    Hermaphroditus
  61. Lab test used to evaluate for CAH
    17 hydroxy progesterone
  62. Highest carrier frequency of CAH
    Yupic Eskimo
  63. Steroid treatment hated by pregnant women at risk for baby with CAH
    Dexamethasone
  64. Novel by Jeffrey Euginides
    Middlesex
  65. Accounts for 5-8% of CAH cases
    11 beta hydroxylase
  66. Non-classic forms of 21 Hydroxylase deficiency are usually this genetic mixture
    Compound heterozygote