Autosomal- recessive 1 in 300 carriers Optic atrophy PP6D5 polymer Proteolytic processing Dysphasia αR424 Gastrostomy tube Isozymes Catalytic dysfunction Chromosome 15q13.3 Warren Sachs GM3- gangliosidosis β- hexosaminidase A Miglustat Substrate reduction therapy Autosomal- dominant Lysosomal storage metabolic disorder Flexible loop HEXA gene GM2 ganglioside depletion Hebephrenic schizophrenia Founder effect GM2- gangliosidosis Hypomyelination HexB deficiency Cherry- red spot Warren Tay AAV vectors GM3 ganglioside accumulation Lysosomes Bernard Tay Neuronal cells N- acetylneuraminic acid Infantile form Chromosome 5q13.3 Homodimeric Hydrolysis White matter Chromosome 15q23 Blood- brain barrier GM2 activator protein GM2 ganglioside accumulation Grey matter Microglia N- acetylgalactosamine Partial deletions Infantile TSD = high HexA levels Neuroglia Juvenile TSD = most severe Epileptic spasms HexA α- subunit Glycosphingolipid Gross deletion Ataxia iPSC cells GLUT1 HPβCD Adult TSD = low HexA levels Missense mutations Aspiration pneumonia c.533 G > A HEXB = chromosome 15 Decerebrate posturing Autosomal- recessive 1 in 300 carriers Optic atrophy PP6D5 polymer Proteolytic processing Dysphasia αR424 Gastrostomy tube Isozymes Catalytic dysfunction Chromosome 15q13.3 Warren Sachs GM3- gangliosidosis β- hexosaminidase A Miglustat Substrate reduction therapy Autosomal- dominant Lysosomal storage metabolic disorder Flexible loop HEXA gene GM2 ganglioside depletion Hebephrenic schizophrenia Founder effect GM2- gangliosidosis Hypomyelination HexB deficiency Cherry- red spot Warren Tay AAV vectors GM3 ganglioside accumulation Lysosomes Bernard Tay Neuronal cells N- acetylneuraminic acid Infantile form Chromosome 5q13.3 Homodimeric Hydrolysis White matter Chromosome 15q23 Blood- brain barrier GM2 activator protein GM2 ganglioside accumulation Grey matter Microglia N- acetylgalactosamine Partial deletions Infantile TSD = high HexA levels Neuroglia Juvenile TSD = most severe Epileptic spasms HexA α- subunit Glycosphingolipid Gross deletion Ataxia iPSC cells GLUT1 HPβCD Adult TSD = low HexA levels Missense mutations Aspiration pneumonia c.533 G > A HEXB = chromosome 15 Decerebrate posturing
(Print) Use this randomly generated list as your call list when playing the game. There is no need to say the BINGO column name. Place some kind of mark (like an X, a checkmark, a dot, tally mark, etc) on each cell as you announce it, to keep track. You can also cut out each item, place them in a bag and pull words from the bag.
Autosomal-recessive
1 in 300 carriers
Optic atrophy
PP6D5 polymer
Proteolytic processing
Dysphasia
αR424
Gastrostomy tube
Isozymes
Catalytic dysfunction
Chromosome 15q13.3
Warren Sachs
GM3-gangliosidosis
β-hexosaminidase A
Miglustat
Substrate reduction therapy
Autosomal-dominant
Lysosomal storage metabolic disorder
Flexible loop
HEXA gene
GM2 ganglioside depletion
Hebephrenic schizophrenia
Founder effect
GM2-gangliosidosis
Hypomyelination
HexB deficiency
Cherry-red spot
Warren Tay
AAV vectors
GM3 ganglioside accumulation
Lysosomes
Bernard Tay
Neuronal cells
N-acetylneuraminic acid
Infantile form
Chromosome 5q13.3
Homodimeric
Hydrolysis
White matter
Chromosome 15q23
Blood-brain barrier
GM2 activator protein
GM2 ganglioside accumulation
Grey matter
Microglia
N-acetylgalactosamine
Partial deletions
Infantile TSD = high HexA levels
Neuroglia
Juvenile TSD = most severe
Epileptic spasms
HexA α-subunit
Glycosphingolipid
Gross deletion
Ataxia
iPSC cells
GLUT1
HPβCD
Adult TSD = low HexA levels
Missense mutations
Aspiration pneumonia
c.533 G > A
HEXB = chromosome 15
Decerebrate posturing