AAV vectors Neuroglia Microglia Chromosome 15q13.3 Founder effect Flexible loop Lysosomal storage metabolic disorder Juvenile TSD = most severe Substrate reduction therapy αR424 Blood- brain barrier Partial deletions PP6D5 polymer Hebephrenic schizophrenia Gross deletion N- acetylgalactosamine N- acetylneuraminic acid Homodimeric Chromosome 15q23 Autosomal- recessive GM2 ganglioside accumulation Isozymes GM2 activator protein Optic atrophy Decerebrate posturing Epileptic spasms Miglustat Catalytic dysfunction Lysosomes Grey matter β- hexosaminidase A Chromosome 5q13.3 GLUT1 HexA α- subunit HexB deficiency Missense mutations Adult TSD = low HexA levels GM3- gangliosidosis iPSC cells Infantile form HPβCD Dysphasia GM2 ganglioside depletion Cherry- red spot HEXB = chromosome 15 Proteolytic processing Hypomyelination Glycosphingolipid Autosomal- dominant c.533 G > A Warren Tay GM2- gangliosidosis Neuronal cells 1 in 300 carriers Warren Sachs Hydrolysis GM3 ganglioside accumulation Aspiration pneumonia HEXA gene White matter Infantile TSD = high HexA levels Gastrostomy tube Bernard Tay Ataxia AAV vectors Neuroglia Microglia Chromosome 15q13.3 Founder effect Flexible loop Lysosomal storage metabolic disorder Juvenile TSD = most severe Substrate reduction therapy αR424 Blood- brain barrier Partial deletions PP6D5 polymer Hebephrenic schizophrenia Gross deletion N- acetylgalactosamine N- acetylneuraminic acid Homodimeric Chromosome 15q23 Autosomal- recessive GM2 ganglioside accumulation Isozymes GM2 activator protein Optic atrophy Decerebrate posturing Epileptic spasms Miglustat Catalytic dysfunction Lysosomes Grey matter β- hexosaminidase A Chromosome 5q13.3 GLUT1 HexA α- subunit HexB deficiency Missense mutations Adult TSD = low HexA levels GM3- gangliosidosis iPSC cells Infantile form HPβCD Dysphasia GM2 ganglioside depletion Cherry- red spot HEXB = chromosome 15 Proteolytic processing Hypomyelination Glycosphingolipid Autosomal- dominant c.533 G > A Warren Tay GM2- gangliosidosis Neuronal cells 1 in 300 carriers Warren Sachs Hydrolysis GM3 ganglioside accumulation Aspiration pneumonia HEXA gene White matter Infantile TSD = high HexA levels Gastrostomy tube Bernard Tay Ataxia
(Print) Use this randomly generated list as your call list when playing the game. There is no need to say the BINGO column name. Place some kind of mark (like an X, a checkmark, a dot, tally mark, etc) on each cell as you announce it, to keep track. You can also cut out each item, place them in a bag and pull words from the bag.
AAV vectors
Neuroglia
Microglia
Chromosome 15q13.3
Founder effect
Flexible loop
Lysosomal storage metabolic disorder
Juvenile TSD = most severe
Substrate reduction therapy
αR424
Blood-brain barrier
Partial deletions
PP6D5 polymer
Hebephrenic schizophrenia
Gross deletion
N-acetylgalactosamine
N-acetylneuraminic acid
Homodimeric
Chromosome 15q23
Autosomal-recessive
GM2 ganglioside accumulation
Isozymes
GM2 activator protein
Optic atrophy
Decerebrate posturing
Epileptic spasms
Miglustat
Catalytic dysfunction
Lysosomes
Grey matter
β-hexosaminidase A
Chromosome 5q13.3
GLUT1
HexA α-subunit
HexB deficiency
Missense mutations
Adult TSD = low HexA levels
GM3-gangliosidosis
iPSC cells
Infantile form
HPβCD
Dysphasia
GM2 ganglioside depletion
Cherry-red spot
HEXB = chromosome 15
Proteolytic processing
Hypomyelination
Glycosphingolipid
Autosomal-dominant
c.533 G > A
Warren Tay
GM2-gangliosidosis
Neuronal cells
1 in 300 carriers
Warren Sachs
Hydrolysis
GM3 ganglioside accumulation
Aspiration pneumonia
HEXA gene
White matter
Infantile TSD = high HexA levels
Gastrostomy tube
Bernard Tay
Ataxia