Chapter 10 Drug Therapy for Dyslipidemia - Call List

(Print) Use this randomly generated list as your call list when playing the game. Place some kind of mark (like an X, a checkmark, a dot, tally mark, etc) on each cell as you announce it, to keep track. You can also cut out each item, place them in a bag and pull words from the bag.

1. H-substances you can mix cholestyramine powder with
   H-Water, other fluids, soups, cereals, or fruits
2. M-Medication belonging to the drug class Cholesterol Absorption Inhibitor
   M-Ezetimibe
3. G-Which medications are considered first-line therapy in the treatment of dyslipidemia in children?
   G-Statins
4. P-Adverse effects of Alirocumab
   P-Nasopharyngitis itching influenza muscle pain diarrhea serious allergic reactions
5. R-Adverse effects of Ezetimibe
   R-Headache Dizziness Fatigue Diarrhea Abdominal pain
6. A-cholestyramine is not absorbed systemically and it may decrease absorption of many oral medications.
   A-True
7. A-Therapeutic response time of Ezetimibe
   A-2 weeks
8. G-acts in the small intestine to inhibit absorption of cholesterol and decrease the delivery of intestinal cholesterol to the liver
   G-Action of Ezetimibe
9. G-Herbs shown to produce a decrease in LDL cholesterol
   G-Flaxseed Flaxseed ligans
10. A-True or False: It is ok for Cholestyramine to be taken in a dry form
    A-False
11. R-Medications in the drug class Fibrates
    R-Fenofibrate Gemfibrozil
12. O-route of administration of Alirocumab
    O-Subcutaneous injection
13. M-Which enzyme do the statins inhibit?
    M-HMG-CoA reductase
14. R-How should someone taking antacids take their prescribed statin?
    R-2 hours before or after antacids
15. P-Ezetimibe is administered with what regard to food?
    P-with or without food
16. M-Adverse effects of Niacin
    M-increase blood sugar skin flushing pruritus GI irritation tachycardia hypotension dizziness
17. O-myopathies, myalgias, myositis, and muscle injury; more commonly - nausea, diarrhea, abdominal pain, dyspepsia, and elevated liver function tests
    O-adverse effects of statins
18. G-increases the oxidation of fatty acids in liver and muscle tissue thus decreasing hepatic production of triglycerides, decrease VLDL cholesterol, and increase HDL cholesterol.
    G-Action of fenofibrate
19. O-Can patients with mild hepatic impairment take Ezetimibe?
    O-Yes, dosage adjustment is necessary
20. R-a vitamin that is no longer recommended as a dyslipidemic agent except in patients with high triglyceride levels (greater than 500 m/dL)
    R-Niacin
21. G-Medications in the drug class Bile Acid Sequestrants
    G-Cholestyramine Colesevelam Colestipol
22. G-promote modulation of the receptor that clears cholesterol, thereby prolong the receptor activity and promoting the clearance of cholesterol
    G-Action of PCSK9 inhibitors
23. M-Medications in the drug class PCSK9 Inhibitors
    M-Alirocumab Evolocumab
24. M-Determining patient's Risk factors, history, smoking history, and comorbidities are part of which nursing process?
    M-Assessment
25. G-Action statements such as helping patient control risk factors, requesting counseling/smoking cessations programs, administering medications per provider orders, educating patinet and family on disease processes,e tc.
    G-Nursing Interventions
26. O-Is fenofibrate given with food or without food? It is necessary to give fenofibrate this way to increase drug absorption
    O-with food
27. P-Main adverse effects are GI - abdominal fullness, flatulence, diarrhea, and constipation
    P-Adverse effect of Cholestyramine
28. A-Fenofibrate given with warfarin or other oral anticoagulants
    A-drug interaction increasing risk of bleeding
29. M-Avoid taking statins with this liquid
    M-grapefruit juice
30. H-myopathy, rhabdomyolysis, blood dyscrasias, hepatotoxicity, cholelithiasis, cholestatic jaundice, pancreatitis, and reduced libido
    H-Rare adverse effects of fenofibrate
31. P-A disorder of lipoprotein metabolism that causes abnormal lipid levels in the blood
    P-Dyslipidemia
32. P-what is the onset of therapeutic effects of statins
    P-1-2 weeks with maximum effect in 4-6 weeks
33. H-Contraindications of Ezetimibe
    H-Pregnancy Lactation Concomitant use with a statin in patients with active hepatic disease
34. H-Lab that is recommended before starting a statin, at 12 weeks after staring the drug, and at every increase in dose, then periodically.
    H-Liver function test
35. A-timeframe for maximum effect to begin for patients on Alirocumab
    A-1 week
36. R-Patient education for cholestyramine - Good oral hygiene needed because holding the mixture int he mouth can cause this...
    R-damages the teeth
37. P-Therapeutic effect of fenofibrate is occur in approximately this timeframe
    P-1 month
38. H-Bile Acid Sequestrants
    H-may be used during pregnancy if needed to lower cholesterol
39. M-peak effect of fenofibrate
    M-6 to 8 hours
40. P-Statin with the highest rate of absorption
    P-Fluvastatin
41. H-subcutaneous injection sites
    H-upper arm abdomen thigh
42. O-binds bile acids int he intestinal lumen, causing the bile acids to be excreted in feces, preventing recirculation to the liver.
    O-Action of Cholestyramine
43. R-This medication demonstrates the most favorable benefit-cost ratio of the four commonly used statin drugs.
    R-Atorvastatin
44. O-observing and validating outcomes and interventions
    O-Evaluation
45. H-carry lipids in blood by binding to specific proteins in plasma
    H-Lipoproteins
46. A-Drugs belonging to the drug class HMG-CoA Reductase Inhibitors
    A-Atorvastatin Fluvastatin Lovastatin Pravastatin Rosuvastatin
47. A-Primary prevention of cardiovascular risk factors associated with dyslipidemia
    A-Healthy Lifestyle
48. O-adverse effect that the patient should notify health care provider for
    O-Patient develops cola-colored urine while on a statin