Myeloperoxidase Myeloblasts are strongly positive with this stain. Hairy Cell Known for causing a dry tap when collecting bone marrow. ALL Children often have a limp caused by this leukemia Blasts You will see an increase in these types of cells in acute leukemia AML Uric Acid & LDH levels are markedly increased CBC Which test is performed first in identifying Leukemias Thrombocyto- penia This is seen in acute leukemias and is a term used to describe decreased platelets. Nucleoli You will see this in immature blast cells. Sudan Black B Stains lipids in myeloblasts ≥20% How many blasts do patients with AML need to have to be a true AML Acute basophilic leukemia Patients experience “hyperhistaminemia” and cutaneous skin lesions Acute Leukemia Will see at least 20% blasts in this type of Leukemia. Pancytopenia Term to describe a decrease in all cell lines Lymphomas Word used to describe when the leukemia only involves lymphocytes. CML Least common of chronic leukemias TRAP Used to diagnosis hairy cell leukemia Chronic Leukemia Individuals can live up to 10 years with this type of leukemia Biphenotypic cells showing myeloid and lymphoid features in the same cell is called what Auer Rods Purple sticks found in the cytoplasm of myeloblasts LAP This stain is used to differentiate between CML and a Leukamoid reaction. Tdt Stains immature lymphoid cells Trisomy 12 CLL will have a genetic abnormality that has an extra chromosome 12 called what All T-cell positive for CD3 and CD7 PAS cytochemistry stain is Positive in 70% of ALL (B-cell type) patients 30% What percentage (%) of patients with Chronic Lymphocytic Leukemia (CLL) will have autoimmune hemolytic anemia? CLL See smudge cells and a positive DAT WHO Current leukemia classification system name ALL B-cell positive for CD10, CD19, CD20, CD22, CD24, and CD79a Immunopheno- typing Correct identification of leukemias are increased to 95% because of what Pure erythroid leukemia Will see Pronormoblasts (RBC precursors), ringed sideroblasts & a positive PAS cytochemical stain Slow Onset This is the kind of onset seen in chronic leukemias. ≥25% How many blasts do patients with ALL need to have to be a true ALL Hepatospleno- megaly Term to describe enlarged spleen and liver Abrupt Onset The is the type of onset that is seen in acute leukemias. Oncogene A mutant gene Nonspecific esterase Monoblasts are strongly positive with this stain Acute Panmyelosis w/ Myelofibrosis In which Acute leukemia will you See Pancytopenia Smudge Cells Fragile cells that break apart when making a slide t(9,22) B – lymphoblastic leukemia/lymphoma patients are known for having this genetic abnormality. Philadelphia Chromosome This chromosome is found in patients that have CML Myeloperoxidase Myeloblasts are strongly positive with this stain. Hairy Cell Known for causing a dry tap when collecting bone marrow. ALL Children often have a limp caused by this leukemia Blasts You will see an increase in these types of cells in acute leukemia AML Uric Acid & LDH levels are markedly increased CBC Which test is performed first in identifying Leukemias Thrombocyto- penia This is seen in acute leukemias and is a term used to describe decreased platelets. Nucleoli You will see this in immature blast cells. Sudan Black B Stains lipids in myeloblasts ≥20% How many blasts do patients with AML need to have to be a true AML Acute basophilic leukemia Patients experience “hyperhistaminemia” and cutaneous skin lesions Acute Leukemia Will see at least 20% blasts in this type of Leukemia. Pancytopenia Term to describe a decrease in all cell lines Lymphomas Word used to describe when the leukemia only involves lymphocytes. CML Least common of chronic leukemias TRAP Used to diagnosis hairy cell leukemia Chronic Leukemia Individuals can live up to 10 years with this type of leukemia Biphenotypic cells showing myeloid and lymphoid features in the same cell is called what Auer Rods Purple sticks found in the cytoplasm of myeloblasts LAP This stain is used to differentiate between CML and a Leukamoid reaction. Tdt Stains immature lymphoid cells Trisomy 12 CLL will have a genetic abnormality that has an extra chromosome 12 called what All T-cell positive for CD3 and CD7 PAS cytochemistry stain is Positive in 70% of ALL (B-cell type) patients 30% What percentage (%) of patients with Chronic Lymphocytic Leukemia (CLL) will have autoimmune hemolytic anemia? CLL See smudge cells and a positive DAT WHO Current leukemia classification system name ALL B-cell positive for CD10, CD19, CD20, CD22, CD24, and CD79a Immunopheno- typing Correct identification of leukemias are increased to 95% because of what Pure erythroid leukemia Will see Pronormoblasts (RBC precursors), ringed sideroblasts & a positive PAS cytochemical stain Slow Onset This is the kind of onset seen in chronic leukemias. ≥25% How many blasts do patients with ALL need to have to be a true ALL Hepatospleno- megaly Term to describe enlarged spleen and liver Abrupt Onset The is the type of onset that is seen in acute leukemias. Oncogene A mutant gene Nonspecific esterase Monoblasts are strongly positive with this stain Acute Panmyelosis w/ Myelofibrosis In which Acute leukemia will you See Pancytopenia Smudge Cells Fragile cells that break apart when making a slide t(9,22) B – lymphoblastic leukemia/lymphoma patients are known for having this genetic abnormality. Philadelphia Chromosome This chromosome is found in patients that have CML
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Myeloblasts are strongly positive with this stain.
Known for causing a dry tap when collecting bone marrow.
Children often have a limp caused by this leukemia
You will see an increase in these types of cells in acute leukemia
Uric Acid & LDH levels are markedly increased
Which test is performed first in identifying Leukemias
This is seen in acute leukemias and is a term used to describe decreased platelets.
You will see this in immature blast cells.
Stains lipids in myeloblasts
How many blasts do patients with AML need to have to be a true AML
Patients experience “hyperhistaminemia” and cutaneous skin
lesions
Will see at least 20% blasts in this type of Leukemia.
Term to describe a decrease in all cell lines
Word used to describe when the leukemia only involves lymphocytes.
Least common of chronic leukemias
Used to diagnosis hairy cell leukemia
Individuals can live up to 10 years with this type of leukemia
cells showing myeloid and lymphoid
features in the same cell is called what
Purple sticks found in the cytoplasm of myeloblasts
This stain is used to differentiate between CML and a Leukamoid reaction.
Stains immature lymphoid cells
CLL will have a genetic abnormality that has an extra chromosome 12 called what
positive for CD3 and CD7
cytochemistry stain is Positive in 70% of ALL (B-cell type) patients
What percentage (%) of patients with Chronic Lymphocytic Leukemia (CLL) will have autoimmune hemolytic anemia?
See smudge cells and a positive DAT
Current leukemia classification system name
positive for CD10, CD19, CD20, CD22,
CD24, and CD79a
Correct identification of leukemias are increased to 95% because of what
Will see Pronormoblasts (RBC precursors), ringed sideroblasts & a positive PAS cytochemical stain
This is the kind of onset seen in chronic leukemias.
How many blasts do patients with ALL need to have to be a true ALL
Term to describe enlarged spleen and liver
The is the type of onset that is seen in acute leukemias.
A mutant gene
Monoblasts are strongly positive with this stain
In which Acute leukemia will you See Pancytopenia
Fragile cells that break apart when making a slide
B – lymphoblastic leukemia/lymphoma patients are known for having this genetic abnormality.
This chromosome is found in patients that have CML
