ALL Children often have a limp caused by this leukemia Oncogene A mutant gene Smudge Cells Fragile cells that break apart when making a slide Slow Onset This is the kind of onset seen in chronic leukemias. Philadelphia Chromosome This chromosome is found in patients that have CML Immunopheno- typing Correct identification of leukemias are increased to 95% because of what LAP This stain is used to differentiate between CML and a Leukamoid reaction. AML Uric Acid & LDH levels are markedly increased Abrupt Onset The is the type of onset that is seen in acute leukemias. Chronic Leukemia Individuals can live up to 10 years with this type of leukemia ALL B-cell positive for CD10, CD19, CD20, CD22, CD24, and CD79a Acute basophilic leukemia Patients experience “hyperhistaminemia” and cutaneous skin lesions Acute Panmyelosis w/ Myelofibrosis In which Acute leukemia will you See Pancytopenia Thrombocyto- penia This is seen in acute leukemias and is a term used to describe decreased platelets. 30% What percentage (%) of patients with Chronic Lymphocytic Leukemia (CLL) will have autoimmune hemolytic anemia? Pancytopenia Term to describe a decrease in all cell lines Tdt Stains immature lymphoid cells All T-cell positive for CD3 and CD7 Myeloperoxidase Myeloblasts are strongly positive with this stain. Lymphomas Word used to describe when the leukemia only involves lymphocytes. Blasts You will see an increase in these types of cells in acute leukemia ≥20% How many blasts do patients with AML need to have to be a true AML CBC Which test is performed first in identifying Leukemias Sudan Black B Stains lipids in myeloblasts Nucleoli You will see this in immature blast cells. WHO Current leukemia classification system name ≥25% How many blasts do patients with ALL need to have to be a true ALL Biphenotypic cells showing myeloid and lymphoid features in the same cell is called what Auer Rods Purple sticks found in the cytoplasm of myeloblasts Acute Leukemia Will see at least 20% blasts in this type of Leukemia. Nonspecific esterase Monoblasts are strongly positive with this stain CLL See smudge cells and a positive DAT TRAP Used to diagnosis hairy cell leukemia CML Least common of chronic leukemias Hairy Cell Known for causing a dry tap when collecting bone marrow. Hepatospleno- megaly Term to describe enlarged spleen and liver Trisomy 12 CLL will have a genetic abnormality that has an extra chromosome 12 called what Pure erythroid leukemia Will see Pronormoblasts (RBC precursors), ringed sideroblasts & a positive PAS cytochemical stain PAS cytochemistry stain is Positive in 70% of ALL (B-cell type) patients t(9,22) B – lymphoblastic leukemia/lymphoma patients are known for having this genetic abnormality. ALL Children often have a limp caused by this leukemia Oncogene A mutant gene Smudge Cells Fragile cells that break apart when making a slide Slow Onset This is the kind of onset seen in chronic leukemias. Philadelphia Chromosome This chromosome is found in patients that have CML Immunopheno- typing Correct identification of leukemias are increased to 95% because of what LAP This stain is used to differentiate between CML and a Leukamoid reaction. AML Uric Acid & LDH levels are markedly increased Abrupt Onset The is the type of onset that is seen in acute leukemias. Chronic Leukemia Individuals can live up to 10 years with this type of leukemia ALL B-cell positive for CD10, CD19, CD20, CD22, CD24, and CD79a Acute basophilic leukemia Patients experience “hyperhistaminemia” and cutaneous skin lesions Acute Panmyelosis w/ Myelofibrosis In which Acute leukemia will you See Pancytopenia Thrombocyto- penia This is seen in acute leukemias and is a term used to describe decreased platelets. 30% What percentage (%) of patients with Chronic Lymphocytic Leukemia (CLL) will have autoimmune hemolytic anemia? Pancytopenia Term to describe a decrease in all cell lines Tdt Stains immature lymphoid cells All T-cell positive for CD3 and CD7 Myeloperoxidase Myeloblasts are strongly positive with this stain. Lymphomas Word used to describe when the leukemia only involves lymphocytes. Blasts You will see an increase in these types of cells in acute leukemia ≥20% How many blasts do patients with AML need to have to be a true AML CBC Which test is performed first in identifying Leukemias Sudan Black B Stains lipids in myeloblasts Nucleoli You will see this in immature blast cells. WHO Current leukemia classification system name ≥25% How many blasts do patients with ALL need to have to be a true ALL Biphenotypic cells showing myeloid and lymphoid features in the same cell is called what Auer Rods Purple sticks found in the cytoplasm of myeloblasts Acute Leukemia Will see at least 20% blasts in this type of Leukemia. Nonspecific esterase Monoblasts are strongly positive with this stain CLL See smudge cells and a positive DAT TRAP Used to diagnosis hairy cell leukemia CML Least common of chronic leukemias Hairy Cell Known for causing a dry tap when collecting bone marrow. Hepatospleno- megaly Term to describe enlarged spleen and liver Trisomy 12 CLL will have a genetic abnormality that has an extra chromosome 12 called what Pure erythroid leukemia Will see Pronormoblasts (RBC precursors), ringed sideroblasts & a positive PAS cytochemical stain PAS cytochemistry stain is Positive in 70% of ALL (B-cell type) patients t(9,22) B – lymphoblastic leukemia/lymphoma patients are known for having this genetic abnormality.
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Children often have a limp caused by this leukemia
A mutant gene
Fragile cells that break apart when making a slide
This is the kind of onset seen in chronic leukemias.
This chromosome is found in patients that have CML
Correct identification of leukemias are increased to 95% because of what
This stain is used to differentiate between CML and a Leukamoid reaction.
Uric Acid & LDH levels are markedly increased
The is the type of onset that is seen in acute leukemias.
Individuals can live up to 10 years with this type of leukemia
positive for CD10, CD19, CD20, CD22,
CD24, and CD79a
Patients experience “hyperhistaminemia” and cutaneous skin
lesions
In which Acute leukemia will you See Pancytopenia
This is seen in acute leukemias and is a term used to describe decreased platelets.
What percentage (%) of patients with Chronic Lymphocytic Leukemia (CLL) will have autoimmune hemolytic anemia?
Term to describe a decrease in all cell lines
Stains immature lymphoid cells
positive for CD3 and CD7
Myeloblasts are strongly positive with this stain.
Word used to describe when the leukemia only involves lymphocytes.
You will see an increase in these types of cells in acute leukemia
How many blasts do patients with AML need to have to be a true AML
Which test is performed first in identifying Leukemias
Stains lipids in myeloblasts
You will see this in immature blast cells.
Current leukemia classification system name
How many blasts do patients with ALL need to have to be a true ALL
cells showing myeloid and lymphoid
features in the same cell is called what
Purple sticks found in the cytoplasm of myeloblasts
Will see at least 20% blasts in this type of Leukemia.
Monoblasts are strongly positive with this stain
See smudge cells and a positive DAT
Used to diagnosis hairy cell leukemia
Least common of chronic leukemias
Known for causing a dry tap when collecting bone marrow.
Term to describe enlarged spleen and liver
CLL will have a genetic abnormality that has an extra chromosome 12 called what
Will see Pronormoblasts (RBC precursors), ringed sideroblasts & a positive PAS cytochemical stain
cytochemistry stain is Positive in 70% of ALL (B-cell type) patients
B – lymphoblastic leukemia/lymphoma patients are known for having this genetic abnormality.
