WHO Current leukemia classification system name Myeloperoxidase Myeloblasts are strongly positive with this stain. All T-cell positive for CD3 and CD7 Biphenotypic cells showing myeloid and lymphoid features in the same cell is called what CLL See smudge cells and a positive DAT Pancytopenia Term to describe a decrease in all cell lines ALL B-cell positive for CD10, CD19, CD20, CD22, CD24, and CD79a ALL Children often have a limp caused by this leukemia Hairy Cell Known for causing a dry tap when collecting bone marrow. Nonspecific esterase Monoblasts are strongly positive with this stain CML Least common of chronic leukemias LAP This stain is used to differentiate between CML and a Leukamoid reaction. Nucleoli You will see this in immature blast cells. Auer Rods Purple sticks found in the cytoplasm of myeloblasts Slow Onset This is the kind of onset seen in chronic leukemias. Philadelphia Chromosome This chromosome is found in patients that have CML Blasts You will see an increase in these types of cells in acute leukemia TRAP Used to diagnosis hairy cell leukemia Acute Panmyelosis w/ Myelofibrosis In which Acute leukemia will you See Pancytopenia Acute basophilic leukemia Patients experience “hyperhistaminemia” and cutaneous skin lesions Chronic Leukemia Individuals can live up to 10 years with this type of leukemia Lymphomas Word used to describe when the leukemia only involves lymphocytes. Trisomy 12 CLL will have a genetic abnormality that has an extra chromosome 12 called what Tdt Stains immature lymphoid cells 30% What percentage (%) of patients with Chronic Lymphocytic Leukemia (CLL) will have autoimmune hemolytic anemia? Immunopheno- typing Correct identification of leukemias are increased to 95% because of what Acute Leukemia Will see at least 20% blasts in this type of Leukemia. Thrombocyto- penia This is seen in acute leukemias and is a term used to describe decreased platelets. CBC Which test is performed first in identifying Leukemias ≥20% How many blasts do patients with AML need to have to be a true AML Oncogene A mutant gene Pure erythroid leukemia Will see Pronormoblasts (RBC precursors), ringed sideroblasts & a positive PAS cytochemical stain t(9,22) B – lymphoblastic leukemia/lymphoma patients are known for having this genetic abnormality. Sudan Black B Stains lipids in myeloblasts Hepatospleno- megaly Term to describe enlarged spleen and liver AML Uric Acid & LDH levels are markedly increased Smudge Cells Fragile cells that break apart when making a slide PAS cytochemistry stain is Positive in 70% of ALL (B-cell type) patients Abrupt Onset The is the type of onset that is seen in acute leukemias. ≥25% How many blasts do patients with ALL need to have to be a true ALL WHO Current leukemia classification system name Myeloperoxidase Myeloblasts are strongly positive with this stain. All T-cell positive for CD3 and CD7 Biphenotypic cells showing myeloid and lymphoid features in the same cell is called what CLL See smudge cells and a positive DAT Pancytopenia Term to describe a decrease in all cell lines ALL B-cell positive for CD10, CD19, CD20, CD22, CD24, and CD79a ALL Children often have a limp caused by this leukemia Hairy Cell Known for causing a dry tap when collecting bone marrow. Nonspecific esterase Monoblasts are strongly positive with this stain CML Least common of chronic leukemias LAP This stain is used to differentiate between CML and a Leukamoid reaction. Nucleoli You will see this in immature blast cells. Auer Rods Purple sticks found in the cytoplasm of myeloblasts Slow Onset This is the kind of onset seen in chronic leukemias. Philadelphia Chromosome This chromosome is found in patients that have CML Blasts You will see an increase in these types of cells in acute leukemia TRAP Used to diagnosis hairy cell leukemia Acute Panmyelosis w/ Myelofibrosis In which Acute leukemia will you See Pancytopenia Acute basophilic leukemia Patients experience “hyperhistaminemia” and cutaneous skin lesions Chronic Leukemia Individuals can live up to 10 years with this type of leukemia Lymphomas Word used to describe when the leukemia only involves lymphocytes. Trisomy 12 CLL will have a genetic abnormality that has an extra chromosome 12 called what Tdt Stains immature lymphoid cells 30% What percentage (%) of patients with Chronic Lymphocytic Leukemia (CLL) will have autoimmune hemolytic anemia? Immunopheno- typing Correct identification of leukemias are increased to 95% because of what Acute Leukemia Will see at least 20% blasts in this type of Leukemia. Thrombocyto- penia This is seen in acute leukemias and is a term used to describe decreased platelets. CBC Which test is performed first in identifying Leukemias ≥20% How many blasts do patients with AML need to have to be a true AML Oncogene A mutant gene Pure erythroid leukemia Will see Pronormoblasts (RBC precursors), ringed sideroblasts & a positive PAS cytochemical stain t(9,22) B – lymphoblastic leukemia/lymphoma patients are known for having this genetic abnormality. Sudan Black B Stains lipids in myeloblasts Hepatospleno- megaly Term to describe enlarged spleen and liver AML Uric Acid & LDH levels are markedly increased Smudge Cells Fragile cells that break apart when making a slide PAS cytochemistry stain is Positive in 70% of ALL (B-cell type) patients Abrupt Onset The is the type of onset that is seen in acute leukemias. ≥25% How many blasts do patients with ALL need to have to be a true ALL
(Print)
Current leukemia classification system name
Myeloblasts are strongly positive with this stain.
positive for CD3 and CD7
cells showing myeloid and lymphoid
features in the same cell is called what
See smudge cells and a positive DAT
Term to describe a decrease in all cell lines
positive for CD10, CD19, CD20, CD22,
CD24, and CD79a
Children often have a limp caused by this leukemia
Known for causing a dry tap when collecting bone marrow.
Monoblasts are strongly positive with this stain
Least common of chronic leukemias
This stain is used to differentiate between CML and a Leukamoid reaction.
You will see this in immature blast cells.
Purple sticks found in the cytoplasm of myeloblasts
This is the kind of onset seen in chronic leukemias.
This chromosome is found in patients that have CML
You will see an increase in these types of cells in acute leukemia
Used to diagnosis hairy cell leukemia
In which Acute leukemia will you See Pancytopenia
Patients experience “hyperhistaminemia” and cutaneous skin
lesions
Individuals can live up to 10 years with this type of leukemia
Word used to describe when the leukemia only involves lymphocytes.
CLL will have a genetic abnormality that has an extra chromosome 12 called what
Stains immature lymphoid cells
What percentage (%) of patients with Chronic Lymphocytic Leukemia (CLL) will have autoimmune hemolytic anemia?
Correct identification of leukemias are increased to 95% because of what
Will see at least 20% blasts in this type of Leukemia.
This is seen in acute leukemias and is a term used to describe decreased platelets.
Which test is performed first in identifying Leukemias
How many blasts do patients with AML need to have to be a true AML
A mutant gene
Will see Pronormoblasts (RBC precursors), ringed sideroblasts & a positive PAS cytochemical stain
B – lymphoblastic leukemia/lymphoma patients are known for having this genetic abnormality.
Stains lipids in myeloblasts
Term to describe enlarged spleen and liver
Uric Acid & LDH levels are markedly increased
Fragile cells that break apart when making a slide
cytochemistry stain is Positive in 70% of ALL (B-cell type) patients
The is the type of onset that is seen in acute leukemias.
How many blasts do patients with ALL need to have to be a true ALL
