Lymphomas Word used to describe when the leukemia only involves lymphocytes. Auer Rods Purple sticks found in the cytoplasm of myeloblasts Acute Leukemia Will see at least 20% blasts in this type of Leukemia. Pancytopenia Term to describe a decrease in all cell lines Nucleoli You will see this in immature blast cells. Hepatospleno- megaly Term to describe enlarged spleen and liver CLL See smudge cells and a positive DAT ALL B-cell positive for CD10, CD19, CD20, CD22, CD24, and CD79a Tdt Stains immature lymphoid cells Slow Onset This is the kind of onset seen in chronic leukemias. ALL Children often have a limp caused by this leukemia Trisomy 12 CLL will have a genetic abnormality that has an extra chromosome 12 called what Immunopheno- typing Correct identification of leukemias are increased to 95% because of what CML Least common of chronic leukemias Biphenotypic cells showing myeloid and lymphoid features in the same cell is called what All T-cell positive for CD3 and CD7 ≥20% How many blasts do patients with AML need to have to be a true AML Acute Panmyelosis w/ Myelofibrosis In which Acute leukemia will you See Pancytopenia Acute basophilic leukemia Patients experience “hyperhistaminemia” and cutaneous skin lesions Chronic Leukemia Individuals can live up to 10 years with this type of leukemia Nonspecific esterase Monoblasts are strongly positive with this stain Hairy Cell Known for causing a dry tap when collecting bone marrow. Sudan Black B Stains lipids in myeloblasts WHO Current leukemia classification system name 30% What percentage (%) of patients with Chronic Lymphocytic Leukemia (CLL) will have autoimmune hemolytic anemia? AML Uric Acid & LDH levels are markedly increased Myeloperoxidase Myeloblasts are strongly positive with this stain. LAP This stain is used to differentiate between CML and a Leukamoid reaction. PAS cytochemistry stain is Positive in 70% of ALL (B-cell type) patients Pure erythroid leukemia Will see Pronormoblasts (RBC precursors), ringed sideroblasts & a positive PAS cytochemical stain Smudge Cells Fragile cells that break apart when making a slide Blasts You will see an increase in these types of cells in acute leukemia CBC Which test is performed first in identifying Leukemias TRAP Used to diagnosis hairy cell leukemia Thrombocyto- penia This is seen in acute leukemias and is a term used to describe decreased platelets. t(9,22) B – lymphoblastic leukemia/lymphoma patients are known for having this genetic abnormality. ≥25% How many blasts do patients with ALL need to have to be a true ALL Abrupt Onset The is the type of onset that is seen in acute leukemias. Philadelphia Chromosome This chromosome is found in patients that have CML Oncogene A mutant gene Lymphomas Word used to describe when the leukemia only involves lymphocytes. Auer Rods Purple sticks found in the cytoplasm of myeloblasts Acute Leukemia Will see at least 20% blasts in this type of Leukemia. Pancytopenia Term to describe a decrease in all cell lines Nucleoli You will see this in immature blast cells. Hepatospleno- megaly Term to describe enlarged spleen and liver CLL See smudge cells and a positive DAT ALL B-cell positive for CD10, CD19, CD20, CD22, CD24, and CD79a Tdt Stains immature lymphoid cells Slow Onset This is the kind of onset seen in chronic leukemias. ALL Children often have a limp caused by this leukemia Trisomy 12 CLL will have a genetic abnormality that has an extra chromosome 12 called what Immunopheno- typing Correct identification of leukemias are increased to 95% because of what CML Least common of chronic leukemias Biphenotypic cells showing myeloid and lymphoid features in the same cell is called what All T-cell positive for CD3 and CD7 ≥20% How many blasts do patients with AML need to have to be a true AML Acute Panmyelosis w/ Myelofibrosis In which Acute leukemia will you See Pancytopenia Acute basophilic leukemia Patients experience “hyperhistaminemia” and cutaneous skin lesions Chronic Leukemia Individuals can live up to 10 years with this type of leukemia Nonspecific esterase Monoblasts are strongly positive with this stain Hairy Cell Known for causing a dry tap when collecting bone marrow. Sudan Black B Stains lipids in myeloblasts WHO Current leukemia classification system name 30% What percentage (%) of patients with Chronic Lymphocytic Leukemia (CLL) will have autoimmune hemolytic anemia? AML Uric Acid & LDH levels are markedly increased Myeloperoxidase Myeloblasts are strongly positive with this stain. LAP This stain is used to differentiate between CML and a Leukamoid reaction. PAS cytochemistry stain is Positive in 70% of ALL (B-cell type) patients Pure erythroid leukemia Will see Pronormoblasts (RBC precursors), ringed sideroblasts & a positive PAS cytochemical stain Smudge Cells Fragile cells that break apart when making a slide Blasts You will see an increase in these types of cells in acute leukemia CBC Which test is performed first in identifying Leukemias TRAP Used to diagnosis hairy cell leukemia Thrombocyto- penia This is seen in acute leukemias and is a term used to describe decreased platelets. t(9,22) B – lymphoblastic leukemia/lymphoma patients are known for having this genetic abnormality. ≥25% How many blasts do patients with ALL need to have to be a true ALL Abrupt Onset The is the type of onset that is seen in acute leukemias. Philadelphia Chromosome This chromosome is found in patients that have CML Oncogene A mutant gene
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Word used to describe when the leukemia only involves lymphocytes.
Purple sticks found in the cytoplasm of myeloblasts
Will see at least 20% blasts in this type of Leukemia.
Term to describe a decrease in all cell lines
You will see this in immature blast cells.
Term to describe enlarged spleen and liver
See smudge cells and a positive DAT
positive for CD10, CD19, CD20, CD22,
CD24, and CD79a
Stains immature lymphoid cells
This is the kind of onset seen in chronic leukemias.
Children often have a limp caused by this leukemia
CLL will have a genetic abnormality that has an extra chromosome 12 called what
Correct identification of leukemias are increased to 95% because of what
Least common of chronic leukemias
cells showing myeloid and lymphoid
features in the same cell is called what
positive for CD3 and CD7
How many blasts do patients with AML need to have to be a true AML
In which Acute leukemia will you See Pancytopenia
Patients experience “hyperhistaminemia” and cutaneous skin
lesions
Individuals can live up to 10 years with this type of leukemia
Monoblasts are strongly positive with this stain
Known for causing a dry tap when collecting bone marrow.
Stains lipids in myeloblasts
Current leukemia classification system name
What percentage (%) of patients with Chronic Lymphocytic Leukemia (CLL) will have autoimmune hemolytic anemia?
Uric Acid & LDH levels are markedly increased
Myeloblasts are strongly positive with this stain.
This stain is used to differentiate between CML and a Leukamoid reaction.
cytochemistry stain is Positive in 70% of ALL (B-cell type) patients
Will see Pronormoblasts (RBC precursors), ringed sideroblasts & a positive PAS cytochemical stain
Fragile cells that break apart when making a slide
You will see an increase in these types of cells in acute leukemia
Which test is performed first in identifying Leukemias
Used to diagnosis hairy cell leukemia
This is seen in acute leukemias and is a term used to describe decreased platelets.
B – lymphoblastic leukemia/lymphoma patients are known for having this genetic abnormality.
How many blasts do patients with ALL need to have to be a true ALL
The is the type of onset that is seen in acute leukemias.
This chromosome is found in patients that have CML
A mutant gene
