Philadelphia Chromosome This chromosome is found in patients that have CML CLL See smudge cells and a positive DAT TRAP Used to diagnosis hairy cell leukemia Pancytopenia Term to describe a decrease in all cell lines Hairy Cell Known for causing a dry tap when collecting bone marrow. Slow Onset This is the kind of onset seen in chronic leukemias. WHO Current leukemia classification system name Immunopheno- typing Correct identification of leukemias are increased to 95% because of what ALL B-cell positive for CD10, CD19, CD20, CD22, CD24, and CD79a 30% What percentage (%) of patients with Chronic Lymphocytic Leukemia (CLL) will have autoimmune hemolytic anemia? Lymphomas Word used to describe when the leukemia only involves lymphocytes. Biphenotypic cells showing myeloid and lymphoid features in the same cell is called what Acute Panmyelosis w/ Myelofibrosis In which Acute leukemia will you See Pancytopenia t(9,22) B – lymphoblastic leukemia/lymphoma patients are known for having this genetic abnormality. Sudan Black B Stains lipids in myeloblasts Blasts You will see an increase in these types of cells in acute leukemia LAP This stain is used to differentiate between CML and a Leukamoid reaction. Hepatospleno- megaly Term to describe enlarged spleen and liver AML Uric Acid & LDH levels are markedly increased Acute basophilic leukemia Patients experience “hyperhistaminemia” and cutaneous skin lesions PAS cytochemistry stain is Positive in 70% of ALL (B-cell type) patients Pure erythroid leukemia Will see Pronormoblasts (RBC precursors), ringed sideroblasts & a positive PAS cytochemical stain CBC Which test is performed first in identifying Leukemias Oncogene A mutant gene Smudge Cells Fragile cells that break apart when making a slide Tdt Stains immature lymphoid cells Nonspecific esterase Monoblasts are strongly positive with this stain Acute Leukemia Will see at least 20% blasts in this type of Leukemia. Chronic Leukemia Individuals can live up to 10 years with this type of leukemia Auer Rods Purple sticks found in the cytoplasm of myeloblasts CML Least common of chronic leukemias Nucleoli You will see this in immature blast cells. ALL Children often have a limp caused by this leukemia All T-cell positive for CD3 and CD7 Myeloperoxidase Myeloblasts are strongly positive with this stain. ≥20% How many blasts do patients with AML need to have to be a true AML Trisomy 12 CLL will have a genetic abnormality that has an extra chromosome 12 called what Thrombocyto- penia This is seen in acute leukemias and is a term used to describe decreased platelets. ≥25% How many blasts do patients with ALL need to have to be a true ALL Abrupt Onset The is the type of onset that is seen in acute leukemias. Philadelphia Chromosome This chromosome is found in patients that have CML CLL See smudge cells and a positive DAT TRAP Used to diagnosis hairy cell leukemia Pancytopenia Term to describe a decrease in all cell lines Hairy Cell Known for causing a dry tap when collecting bone marrow. Slow Onset This is the kind of onset seen in chronic leukemias. WHO Current leukemia classification system name Immunopheno- typing Correct identification of leukemias are increased to 95% because of what ALL B-cell positive for CD10, CD19, CD20, CD22, CD24, and CD79a 30% What percentage (%) of patients with Chronic Lymphocytic Leukemia (CLL) will have autoimmune hemolytic anemia? Lymphomas Word used to describe when the leukemia only involves lymphocytes. Biphenotypic cells showing myeloid and lymphoid features in the same cell is called what Acute Panmyelosis w/ Myelofibrosis In which Acute leukemia will you See Pancytopenia t(9,22) B – lymphoblastic leukemia/lymphoma patients are known for having this genetic abnormality. Sudan Black B Stains lipids in myeloblasts Blasts You will see an increase in these types of cells in acute leukemia LAP This stain is used to differentiate between CML and a Leukamoid reaction. Hepatospleno- megaly Term to describe enlarged spleen and liver AML Uric Acid & LDH levels are markedly increased Acute basophilic leukemia Patients experience “hyperhistaminemia” and cutaneous skin lesions PAS cytochemistry stain is Positive in 70% of ALL (B-cell type) patients Pure erythroid leukemia Will see Pronormoblasts (RBC precursors), ringed sideroblasts & a positive PAS cytochemical stain CBC Which test is performed first in identifying Leukemias Oncogene A mutant gene Smudge Cells Fragile cells that break apart when making a slide Tdt Stains immature lymphoid cells Nonspecific esterase Monoblasts are strongly positive with this stain Acute Leukemia Will see at least 20% blasts in this type of Leukemia. Chronic Leukemia Individuals can live up to 10 years with this type of leukemia Auer Rods Purple sticks found in the cytoplasm of myeloblasts CML Least common of chronic leukemias Nucleoli You will see this in immature blast cells. ALL Children often have a limp caused by this leukemia All T-cell positive for CD3 and CD7 Myeloperoxidase Myeloblasts are strongly positive with this stain. ≥20% How many blasts do patients with AML need to have to be a true AML Trisomy 12 CLL will have a genetic abnormality that has an extra chromosome 12 called what Thrombocyto- penia This is seen in acute leukemias and is a term used to describe decreased platelets. ≥25% How many blasts do patients with ALL need to have to be a true ALL Abrupt Onset The is the type of onset that is seen in acute leukemias.
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This chromosome is found in patients that have CML
See smudge cells and a positive DAT
Used to diagnosis hairy cell leukemia
Term to describe a decrease in all cell lines
Known for causing a dry tap when collecting bone marrow.
This is the kind of onset seen in chronic leukemias.
Current leukemia classification system name
Correct identification of leukemias are increased to 95% because of what
positive for CD10, CD19, CD20, CD22,
CD24, and CD79a
What percentage (%) of patients with Chronic Lymphocytic Leukemia (CLL) will have autoimmune hemolytic anemia?
Word used to describe when the leukemia only involves lymphocytes.
cells showing myeloid and lymphoid
features in the same cell is called what
In which Acute leukemia will you See Pancytopenia
B – lymphoblastic leukemia/lymphoma patients are known for having this genetic abnormality.
Stains lipids in myeloblasts
You will see an increase in these types of cells in acute leukemia
This stain is used to differentiate between CML and a Leukamoid reaction.
Term to describe enlarged spleen and liver
Uric Acid & LDH levels are markedly increased
Patients experience “hyperhistaminemia” and cutaneous skin
lesions
cytochemistry stain is Positive in 70% of ALL (B-cell type) patients
Will see Pronormoblasts (RBC precursors), ringed sideroblasts & a positive PAS cytochemical stain
Which test is performed first in identifying Leukemias
A mutant gene
Fragile cells that break apart when making a slide
Stains immature lymphoid cells
Monoblasts are strongly positive with this stain
Will see at least 20% blasts in this type of Leukemia.
Individuals can live up to 10 years with this type of leukemia
Purple sticks found in the cytoplasm of myeloblasts
Least common of chronic leukemias
You will see this in immature blast cells.
Children often have a limp caused by this leukemia
positive for CD3 and CD7
Myeloblasts are strongly positive with this stain.
How many blasts do patients with AML need to have to be a true AML
CLL will have a genetic abnormality that has an extra chromosome 12 called what
This is seen in acute leukemias and is a term used to describe decreased platelets.
How many blasts do patients with ALL need to have to be a true ALL
The is the type of onset that is seen in acute leukemias.
