Acute basophilic leukemia Patients experience “hyperhistaminemia” and cutaneous skin lesions Oncogene A mutant gene Sudan Black B Stains lipids in myeloblasts TRAP Used to diagnosis hairy cell leukemia ≥25% How many blasts do patients with ALL need to have to be a true ALL CLL See smudge cells and a positive DAT Nonspecific esterase Monoblasts are strongly positive with this stain Smudge Cells Fragile cells that break apart when making a slide All T-cell positive for CD3 and CD7 Pancytopenia Term to describe a decrease in all cell lines Hepatospleno- megaly Term to describe enlarged spleen and liver Hairy Cell Known for causing a dry tap when collecting bone marrow. Philadelphia Chromosome This chromosome is found in patients that have CML CBC Which test is performed first in identifying Leukemias Immunopheno- typing Correct identification of leukemias are increased to 95% because of what Pure erythroid leukemia Will see Pronormoblasts (RBC precursors), ringed sideroblasts & a positive PAS cytochemical stain Slow Onset This is the kind of onset seen in chronic leukemias. t(9,22) B – lymphoblastic leukemia/lymphoma patients are known for having this genetic abnormality. ALL Children often have a limp caused by this leukemia AML Uric Acid & LDH levels are markedly increased CML Least common of chronic leukemias Biphenotypic cells showing myeloid and lymphoid features in the same cell is called what Nucleoli You will see this in immature blast cells. Blasts You will see an increase in these types of cells in acute leukemia ALL B-cell positive for CD10, CD19, CD20, CD22, CD24, and CD79a Trisomy 12 CLL will have a genetic abnormality that has an extra chromosome 12 called what Acute Leukemia Will see at least 20% blasts in this type of Leukemia. Chronic Leukemia Individuals can live up to 10 years with this type of leukemia Thrombocyto- penia This is seen in acute leukemias and is a term used to describe decreased platelets. Lymphomas Word used to describe when the leukemia only involves lymphocytes. Auer Rods Purple sticks found in the cytoplasm of myeloblasts ≥20% How many blasts do patients with AML need to have to be a true AML WHO Current leukemia classification system name Abrupt Onset The is the type of onset that is seen in acute leukemias. 30% What percentage (%) of patients with Chronic Lymphocytic Leukemia (CLL) will have autoimmune hemolytic anemia? Tdt Stains immature lymphoid cells LAP This stain is used to differentiate between CML and a Leukamoid reaction. PAS cytochemistry stain is Positive in 70% of ALL (B-cell type) patients Acute Panmyelosis w/ Myelofibrosis In which Acute leukemia will you See Pancytopenia Myeloperoxidase Myeloblasts are strongly positive with this stain. Acute basophilic leukemia Patients experience “hyperhistaminemia” and cutaneous skin lesions Oncogene A mutant gene Sudan Black B Stains lipids in myeloblasts TRAP Used to diagnosis hairy cell leukemia ≥25% How many blasts do patients with ALL need to have to be a true ALL CLL See smudge cells and a positive DAT Nonspecific esterase Monoblasts are strongly positive with this stain Smudge Cells Fragile cells that break apart when making a slide All T-cell positive for CD3 and CD7 Pancytopenia Term to describe a decrease in all cell lines Hepatospleno- megaly Term to describe enlarged spleen and liver Hairy Cell Known for causing a dry tap when collecting bone marrow. Philadelphia Chromosome This chromosome is found in patients that have CML CBC Which test is performed first in identifying Leukemias Immunopheno- typing Correct identification of leukemias are increased to 95% because of what Pure erythroid leukemia Will see Pronormoblasts (RBC precursors), ringed sideroblasts & a positive PAS cytochemical stain Slow Onset This is the kind of onset seen in chronic leukemias. t(9,22) B – lymphoblastic leukemia/lymphoma patients are known for having this genetic abnormality. ALL Children often have a limp caused by this leukemia AML Uric Acid & LDH levels are markedly increased CML Least common of chronic leukemias Biphenotypic cells showing myeloid and lymphoid features in the same cell is called what Nucleoli You will see this in immature blast cells. Blasts You will see an increase in these types of cells in acute leukemia ALL B-cell positive for CD10, CD19, CD20, CD22, CD24, and CD79a Trisomy 12 CLL will have a genetic abnormality that has an extra chromosome 12 called what Acute Leukemia Will see at least 20% blasts in this type of Leukemia. Chronic Leukemia Individuals can live up to 10 years with this type of leukemia Thrombocyto- penia This is seen in acute leukemias and is a term used to describe decreased platelets. Lymphomas Word used to describe when the leukemia only involves lymphocytes. Auer Rods Purple sticks found in the cytoplasm of myeloblasts ≥20% How many blasts do patients with AML need to have to be a true AML WHO Current leukemia classification system name Abrupt Onset The is the type of onset that is seen in acute leukemias. 30% What percentage (%) of patients with Chronic Lymphocytic Leukemia (CLL) will have autoimmune hemolytic anemia? Tdt Stains immature lymphoid cells LAP This stain is used to differentiate between CML and a Leukamoid reaction. PAS cytochemistry stain is Positive in 70% of ALL (B-cell type) patients Acute Panmyelosis w/ Myelofibrosis In which Acute leukemia will you See Pancytopenia Myeloperoxidase Myeloblasts are strongly positive with this stain.
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Patients experience “hyperhistaminemia” and cutaneous skin
lesions
A mutant gene
Stains lipids in myeloblasts
Used to diagnosis hairy cell leukemia
How many blasts do patients with ALL need to have to be a true ALL
See smudge cells and a positive DAT
Monoblasts are strongly positive with this stain
Fragile cells that break apart when making a slide
positive for CD3 and CD7
Term to describe a decrease in all cell lines
Term to describe enlarged spleen and liver
Known for causing a dry tap when collecting bone marrow.
This chromosome is found in patients that have CML
Which test is performed first in identifying Leukemias
Correct identification of leukemias are increased to 95% because of what
Will see Pronormoblasts (RBC precursors), ringed sideroblasts & a positive PAS cytochemical stain
This is the kind of onset seen in chronic leukemias.
B – lymphoblastic leukemia/lymphoma patients are known for having this genetic abnormality.
Children often have a limp caused by this leukemia
Uric Acid & LDH levels are markedly increased
Least common of chronic leukemias
cells showing myeloid and lymphoid
features in the same cell is called what
You will see this in immature blast cells.
You will see an increase in these types of cells in acute leukemia
positive for CD10, CD19, CD20, CD22,
CD24, and CD79a
CLL will have a genetic abnormality that has an extra chromosome 12 called what
Will see at least 20% blasts in this type of Leukemia.
Individuals can live up to 10 years with this type of leukemia
This is seen in acute leukemias and is a term used to describe decreased platelets.
Word used to describe when the leukemia only involves lymphocytes.
Purple sticks found in the cytoplasm of myeloblasts
How many blasts do patients with AML need to have to be a true AML
Current leukemia classification system name
The is the type of onset that is seen in acute leukemias.
What percentage (%) of patients with Chronic Lymphocytic Leukemia (CLL) will have autoimmune hemolytic anemia?
Stains immature lymphoid cells
This stain is used to differentiate between CML and a Leukamoid reaction.
cytochemistry stain is Positive in 70% of ALL (B-cell type) patients
In which Acute leukemia will you See Pancytopenia
Myeloblasts are strongly positive with this stain.
