Philadelphia Chromosome This chromosome is found in patients that have CML ≥25% How many blasts do patients with ALL need to have to be a true ALL CBC Which test is performed first in identifying Leukemias Pancytopenia Term to describe a decrease in all cell lines Tdt Stains immature lymphoid cells Hepatospleno- megaly Term to describe enlarged spleen and liver LAP This stain is used to differentiate between CML and a Leukamoid reaction. Trisomy 12 CLL will have a genetic abnormality that has an extra chromosome 12 called what TRAP Used to diagnosis hairy cell leukemia Sudan Black B Stains lipids in myeloblasts 30% What percentage (%) of patients with Chronic Lymphocytic Leukemia (CLL) will have autoimmune hemolytic anemia? ≥20% How many blasts do patients with AML need to have to be a true AML t(9,22) B – lymphoblastic leukemia/lymphoma patients are known for having this genetic abnormality. Hairy Cell Known for causing a dry tap when collecting bone marrow. Biphenotypic cells showing myeloid and lymphoid features in the same cell is called what Acute Panmyelosis w/ Myelofibrosis In which Acute leukemia will you See Pancytopenia Immunopheno- typing Correct identification of leukemias are increased to 95% because of what Myeloperoxidase Myeloblasts are strongly positive with this stain. Blasts You will see an increase in these types of cells in acute leukemia ALL Children often have a limp caused by this leukemia Abrupt Onset The is the type of onset that is seen in acute leukemias. Auer Rods Purple sticks found in the cytoplasm of myeloblasts Acute basophilic leukemia Patients experience “hyperhistaminemia” and cutaneous skin lesions ALL B-cell positive for CD10, CD19, CD20, CD22, CD24, and CD79a Nucleoli You will see this in immature blast cells. Oncogene A mutant gene Slow Onset This is the kind of onset seen in chronic leukemias. WHO Current leukemia classification system name CLL See smudge cells and a positive DAT Pure erythroid leukemia Will see Pronormoblasts (RBC precursors), ringed sideroblasts & a positive PAS cytochemical stain Acute Leukemia Will see at least 20% blasts in this type of Leukemia. All T-cell positive for CD3 and CD7 Smudge Cells Fragile cells that break apart when making a slide PAS cytochemistry stain is Positive in 70% of ALL (B-cell type) patients Lymphomas Word used to describe when the leukemia only involves lymphocytes. Nonspecific esterase Monoblasts are strongly positive with this stain Thrombocyto- penia This is seen in acute leukemias and is a term used to describe decreased platelets. CML Least common of chronic leukemias Chronic Leukemia Individuals can live up to 10 years with this type of leukemia AML Uric Acid & LDH levels are markedly increased Philadelphia Chromosome This chromosome is found in patients that have CML ≥25% How many blasts do patients with ALL need to have to be a true ALL CBC Which test is performed first in identifying Leukemias Pancytopenia Term to describe a decrease in all cell lines Tdt Stains immature lymphoid cells Hepatospleno- megaly Term to describe enlarged spleen and liver LAP This stain is used to differentiate between CML and a Leukamoid reaction. Trisomy 12 CLL will have a genetic abnormality that has an extra chromosome 12 called what TRAP Used to diagnosis hairy cell leukemia Sudan Black B Stains lipids in myeloblasts 30% What percentage (%) of patients with Chronic Lymphocytic Leukemia (CLL) will have autoimmune hemolytic anemia? ≥20% How many blasts do patients with AML need to have to be a true AML t(9,22) B – lymphoblastic leukemia/lymphoma patients are known for having this genetic abnormality. Hairy Cell Known for causing a dry tap when collecting bone marrow. Biphenotypic cells showing myeloid and lymphoid features in the same cell is called what Acute Panmyelosis w/ Myelofibrosis In which Acute leukemia will you See Pancytopenia Immunopheno- typing Correct identification of leukemias are increased to 95% because of what Myeloperoxidase Myeloblasts are strongly positive with this stain. Blasts You will see an increase in these types of cells in acute leukemia ALL Children often have a limp caused by this leukemia Abrupt Onset The is the type of onset that is seen in acute leukemias. Auer Rods Purple sticks found in the cytoplasm of myeloblasts Acute basophilic leukemia Patients experience “hyperhistaminemia” and cutaneous skin lesions ALL B-cell positive for CD10, CD19, CD20, CD22, CD24, and CD79a Nucleoli You will see this in immature blast cells. Oncogene A mutant gene Slow Onset This is the kind of onset seen in chronic leukemias. WHO Current leukemia classification system name CLL See smudge cells and a positive DAT Pure erythroid leukemia Will see Pronormoblasts (RBC precursors), ringed sideroblasts & a positive PAS cytochemical stain Acute Leukemia Will see at least 20% blasts in this type of Leukemia. All T-cell positive for CD3 and CD7 Smudge Cells Fragile cells that break apart when making a slide PAS cytochemistry stain is Positive in 70% of ALL (B-cell type) patients Lymphomas Word used to describe when the leukemia only involves lymphocytes. Nonspecific esterase Monoblasts are strongly positive with this stain Thrombocyto- penia This is seen in acute leukemias and is a term used to describe decreased platelets. CML Least common of chronic leukemias Chronic Leukemia Individuals can live up to 10 years with this type of leukemia AML Uric Acid & LDH levels are markedly increased
(Print)
This chromosome is found in patients that have CML
How many blasts do patients with ALL need to have to be a true ALL
Which test is performed first in identifying Leukemias
Term to describe a decrease in all cell lines
Stains immature lymphoid cells
Term to describe enlarged spleen and liver
This stain is used to differentiate between CML and a Leukamoid reaction.
CLL will have a genetic abnormality that has an extra chromosome 12 called what
Used to diagnosis hairy cell leukemia
Stains lipids in myeloblasts
What percentage (%) of patients with Chronic Lymphocytic Leukemia (CLL) will have autoimmune hemolytic anemia?
How many blasts do patients with AML need to have to be a true AML
B – lymphoblastic leukemia/lymphoma patients are known for having this genetic abnormality.
Known for causing a dry tap when collecting bone marrow.
cells showing myeloid and lymphoid
features in the same cell is called what
In which Acute leukemia will you See Pancytopenia
Correct identification of leukemias are increased to 95% because of what
Myeloblasts are strongly positive with this stain.
You will see an increase in these types of cells in acute leukemia
Children often have a limp caused by this leukemia
The is the type of onset that is seen in acute leukemias.
Purple sticks found in the cytoplasm of myeloblasts
Patients experience “hyperhistaminemia” and cutaneous skin
lesions
positive for CD10, CD19, CD20, CD22,
CD24, and CD79a
You will see this in immature blast cells.
A mutant gene
This is the kind of onset seen in chronic leukemias.
Current leukemia classification system name
See smudge cells and a positive DAT
Will see Pronormoblasts (RBC precursors), ringed sideroblasts & a positive PAS cytochemical stain
Will see at least 20% blasts in this type of Leukemia.
positive for CD3 and CD7
Fragile cells that break apart when making a slide
cytochemistry stain is Positive in 70% of ALL (B-cell type) patients
Word used to describe when the leukemia only involves lymphocytes.
Monoblasts are strongly positive with this stain
This is seen in acute leukemias and is a term used to describe decreased platelets.
Least common of chronic leukemias
Individuals can live up to 10 years with this type of leukemia
Uric Acid & LDH levels are markedly increased
