(Print) Use this randomly generated list as your call list when playing the game. Place some kind of mark (like an X, a checkmark, a dot, tally mark, etc) on each cell as you announce it, to keep track. You can also cut out each item, place them in a bag and pull words from the bag.
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I-6
B-I2
I-I3
N-A benign glandular epithelial neoplasm is called an:
I-9
O-Answer: ONCOGENE
I-10
G-Answer: N
G-B4
G-* Melanoma
G-Which tumor suppressor gene is commonly called the “guardian of the genome”?
O-22
N-12
O-25
B-2
I-🟨 N — NOMENCLATURE
O-⸻
B-4
G-20
N-🔥 HOTS Question
N-Answer: EXPANSILE GROWTH
B-🟩 G — GRADING & STAGING / TNM
G-16
G-In TNM, what does M represent?
G-Answer: METASTASIS / NO METASTASIS
N-O4
G-What structure must an epithelial carcinoma breach to become invasive?
I-A malignant neoplasm derived from mesenchymal tissue is called a:
N-B3
I-7
N-I4
I-O5
B-A malignant neoplasm derived from epithelial cells is called a:
O-G3
O-B5
O-Benign tumors generally resemble their tissue of origin. What term describes this?
I-Answer: WELL DIFFERENTIATED
I-O3
G-A benign epithelial tumor producing finger-like or wart-like projections is called a:
B-1
I-* Mesothelioma
B-Answer: PAPILLOMA
O-A tumor containing tissues derived from more than one germ cell layer is called a:
N-What is the activated form of a proto-oncogene that promotes uncontrolled proliferation?
N-🟥 I — INVASION & MALIGNANCY
O-O1
O-I1
N-Answer: STAGE
N-A tumor is well circumscribed, slow growing, and remains localized. What type of neoplasm is this?
O-Answer: METASTASIS
G-18
I-8
O-What describes the degree of differentiation and cytologic aggressiveness of a tumor?
I-A normal gene involved in cell growth that can become cancer-promoting after mutation or inappropriate activation is called a:
O-Answer: REGIONAL LYMPH NODE INVOLVEMENT
N-15
G-Answer: PRIMARY TUMOR
B-B1
B-3
O-A carcinoma is surrounded by dense collagenous fibrous tissue produced in response to the tumor. What is this called?
G-Answer: INVASION
N-🟪 O — ONCOGENESIS & MOLECULAR ALTERATIONS
B-What describes the extent of spread of cancer throughout the body?
B-O2
O-Answer: BENIGN
I-Examples of malignant tumors ending in “-oma” include:
B-Ask:
I-N4
B-What process allows a growing tumor to develop its own blood supply?
I-What major feature is absent in typical benign neoplasms?
N-G1
N-N5
N-14
G-N1
N-Answer: CARCINOMA
G-G2
N-11
O-Which proto-oncogene family encodes small GTP-binding proteins and is frequently mutated in cancer? Answer: RAS
O-24
G-⸻
O-A patient has a 3-cm carcinoma with regional lymph-node involvement but no distant metastasis.
N-Is every tumor ending in “-oma” benign?
O-N2
B-N3
I-Answer: TERATOMA
I-Answer: DESMOPLASIA
O-Answer: NO.
G-Answer: SARCOMA
B-Answer: DISTANT METASTASIS
B-Answer: TP53
N-Answer: ANGIOGENESIS
B-Answer: RB
B-5
B-What type of growth pattern is characteristic of many benign tumors?
O-23
G-17
G-I5
B-⸻
B-Answer: ENCAPSULATION
G-Which tumor suppressor gene regulates the G1/S cell-cycle checkpoint?
I-Answer: GRADE
I-In TNM, what does T primarily represent?
B-G4
G-Answer: PROTO-ONCOGENE
O-Answer: ADENOMA
O-21
O-* Lymphoma
I-Which TNM component is represented by the lymph-node involvement?
I-A malignant epithelial tumor penetrates through the basement membrane into the underlying stroma. What process has occurred?
B-* Seminoma
B-⸻
N-Malignant cells establish a secondary tumor in the liver after originating in the colon. What is this called?
N-In TNM, what does N represent?
G-19
I-G5
G-What feature may separate a benign tumor from the surrounding normal tissue?
