Answer:PRIMARYTUMORA carcinoma issurrounded by densecollagenous fibroustissue produced inresponse to thetumor. What is thiscalled?What featuremay separate abenign tumorfrom thesurroundingnormal tissue?Answer:ADENOMA🟨 N —NOMENCLATUREAnswer:PAPILLOMAIs everytumor endingin “-oma”benign?*LymphomaIn TNM,what doesNrepresent?A malignantneoplasmderived fromepithelial cellsis called a:N2Malignant cellsestablish asecondary tumorin the liver afteroriginating in thecolon. What is thiscalled?Benign tumorsgenerallyresemble theirtissue of origin.What termdescribes this?O1N4Answer:ANGIOGENESISAnswer:REGIONALLYMPH NODEINVOLVEMENTAnswer:BASEMENTMEMBRANEI5🟥 I —INVASION &MALIGNANCYAsk:Examples ofmalignanttumorsending in “-oma” include:What describesthe degree ofdifferentiationand cytologicaggressivenessof a tumor?I2Answer:RAS⸻What is theactivated form ofa proto-oncogenethat promotesuncontrolledproliferation?O5In TNM,what doesMrepresent?A tumorcontainingtissues derivedfrom more thanone germ celllayer is called a:Answer:PROTO-ONCOGENEAnswer:INVASION⸻🔥HOTSQuestion⸻In TNM,what doesT primarilyrepresent?Answer:TP53G3⸻*MesotheliomaO3Answer:DISTANTMETASTASISWhich tumorsuppressor geneis commonlycalled the“guardian of thegenome”?G4Answer:NA normal geneinvolved in cellgrowth that canbecome cancer-promoting aftermutation orinappropriateactivation is called a:N5Answer:METASTASIS🟪 O —ONCOGENESIS& MOLECULARALTERATIONSAnswer:STAGEAnswer:DESMOPLASIAA patient has a 3-cm carcinoma withregional lymph-node involvementbut no distantmetastasis.🟩 G —GRADING& STAGING/ TNMA malignant epithelialtumor penetratesthrough thebasement membraneinto the underlyingstroma. Whatprocess hasoccurred?What describesthe extent ofspread ofcancerthroughout thebody?Answer:NO.Which proto-oncogene familyencodes smallGTP-bindingproteins and isfrequently mutatedin cancer?Answer:CARCINOMAG1G5What type ofgrowth patternis characteristicof many benigntumors?O4🔥NomenclatureChallengeA malignantneoplasmderived frommesenchymaltissue is calleda:Which TNMcomponent isrepresented bythe lymph-nodeinvolvement?What processallows agrowing tumorto develop itsown bloodsupply?Answer:SARCOMAI1*MelanomaA benignepithelial tumorproducing finger-like or wart-likeprojections iscalled a:N1I3A benignglandularepithelialneoplasm iscalled an:Answer:RBN3What structuremust an epithelialcarcinomabreach tobecomeinvasive?I4*SeminomaAnswer:GRADEG2A tumor is wellcircumscribed,slow growing, andremains localized.What type ofneoplasm is this?What majorfeature isabsent intypical benignneoplasms?Answer:TERATOMAO2Which tumorsuppressorgene regulatesthe G1/S cell-cyclecheckpoint?Answer:ONCOGENEAnswer:PRIMARYTUMORA carcinoma issurrounded by densecollagenous fibroustissue produced inresponse to thetumor. What is thiscalled?What featuremay separate abenign tumorfrom thesurroundingnormal tissue?Answer:ADENOMA🟨 N —NOMENCLATUREAnswer:PAPILLOMAIs everytumor endingin “-oma”benign?*LymphomaIn TNM,what doesNrepresent?A malignantneoplasmderived fromepithelial cellsis called a:N2Malignant cellsestablish asecondary tumorin the liver afteroriginating in thecolon. What is thiscalled?Benign tumorsgenerallyresemble theirtissue of origin.What termdescribes this?O1N4Answer:ANGIOGENESISAnswer:REGIONALLYMPH NODEINVOLVEMENTAnswer:BASEMENTMEMBRANEI5🟥 I —INVASION &MALIGNANCYAsk:Examples ofmalignanttumorsending in “-oma” include:What describesthe degree ofdifferentiationand cytologicaggressivenessof a tumor?I2Answer:RAS⸻What is theactivated form ofa proto-oncogenethat promotesuncontrolledproliferation?O5In TNM,what doesMrepresent?A tumorcontainingtissues derivedfrom more thanone germ celllayer is called a:Answer:PROTO-ONCOGENEAnswer:INVASION⸻🔥HOTSQuestion⸻In TNM,what doesT primarilyrepresent?Answer:TP53G3⸻*MesotheliomaO3Answer:DISTANTMETASTASISWhich tumorsuppressor geneis commonlycalled the“guardian of thegenome”?G4Answer:NA normal geneinvolved in cellgrowth that canbecome cancer-promoting aftermutation orinappropriateactivation is called a:N5Answer:METASTASIS🟪 O —ONCOGENESIS& MOLECULARALTERATIONSAnswer:STAGEAnswer:DESMOPLASIAA patient has a 3-cm carcinoma withregional lymph-node involvementbut no distantmetastasis.🟩 G —GRADING& STAGING/ TNMA malignant epithelialtumor penetratesthrough thebasement membraneinto the underlyingstroma. Whatprocess hasoccurred?What describesthe extent ofspread ofcancerthroughout thebody?Answer:NO.Which proto-oncogene familyencodes smallGTP-bindingproteins and isfrequently mutatedin cancer?Answer:CARCINOMAG1G5What type ofgrowth patternis characteristicof many benigntumors?O4🔥NomenclatureChallengeA malignantneoplasmderived frommesenchymaltissue is calleda:Which TNMcomponent isrepresented bythe lymph-nodeinvolvement?What processallows agrowing tumorto develop itsown bloodsupply?Answer:SARCOMAI1*MelanomaA benignepithelial tumorproducing finger-like or wart-likeprojections iscalled a:N1I3A benignglandularepithelialneoplasm iscalled an:Answer:RBN3What structuremust an epithelialcarcinomabreach tobecomeinvasive?I4*SeminomaAnswer:GRADEG2A tumor is wellcircumscribed,slow growing, andremains localized.What type ofneoplasm is this?What majorfeature isabsent intypical benignneoplasms?Answer:TERATOMAO2Which tumorsuppressorgene regulatesthe G1/S cell-cyclecheckpoint?Answer:ONCOGENE

Untitled Bingo - Call List

(Print) Use this randomly generated list as your call list when playing the game. There is no need to say the BINGO column name. Place some kind of mark (like an X, a checkmark, a dot, tally mark, etc) on each cell as you announce it, to keep track. You can also cut out each item, place them in a bag and pull words from the bag.


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  1. Answer: PRIMARY TUMOR
  2. A carcinoma is surrounded by dense collagenous fibrous tissue produced in response to the tumor. What is this called?
  3. What feature may separate a benign tumor from the surrounding normal tissue?
  4. Answer: ADENOMA
  5. 🟨 N — NOMENCLATURE
  6. Answer: PAPILLOMA
  7. Is every tumor ending in “-oma” benign?
  8. * Lymphoma
  9. In TNM, what does N represent?
  10. A malignant neoplasm derived from epithelial cells is called a:
  11. N2
  12. Malignant cells establish a secondary tumor in the liver after originating in the colon. What is this called?
  13. Benign tumors generally resemble their tissue of origin. What term describes this?
  14. O1
  15. N4
  16. Answer: ANGIOGENESIS
  17. Answer: REGIONAL LYMPH NODE INVOLVEMENT
  18. Answer: BASEMENT MEMBRANE
  19. I5
  20. 🟥 I — INVASION & MALIGNANCY
  21. Ask:
  22. Examples of malignant tumors ending in “-oma” include:
  23. What describes the degree of differentiation and cytologic aggressiveness of a tumor?
  24. I2
  25. Answer: RAS
  26. ⸻
  27. What is the activated form of a proto-oncogene that promotes uncontrolled proliferation?
  28. O5
  29. In TNM, what does M represent?
  30. A tumor containing tissues derived from more than one germ cell layer is called a:
  31. Answer: PROTO-ONCOGENE
  32. Answer: INVASION
  33. ⸻
  34. 🔥 HOTS Question
  35. ⸻
  36. In TNM, what does T primarily represent?
  37. Answer: TP53
  38. G3
  39. ⸻
  40. * Mesothelioma
  41. O3
  42. Answer: DISTANT METASTASIS
  43. Which tumor suppressor gene is commonly called the “guardian of the genome”?
  44. G4
  45. Answer: N
  46. A normal gene involved in cell growth that can become cancer-promoting after mutation or inappropriate activation is called a:
  47. N5
  48. Answer: METASTASIS
  49. 🟪 O — ONCOGENESIS & MOLECULAR ALTERATIONS
  50. Answer: STAGE
  51. Answer: DESMOPLASIA
  52. A patient has a 3-cm carcinoma with regional lymph-node involvement but no distant metastasis.
  53. 🟩 G — GRADING & STAGING / TNM
  54. A malignant epithelial tumor penetrates through the basement membrane into the underlying stroma. What process has occurred?
  55. What describes the extent of spread of cancer throughout the body?
  56. Answer: NO.
  57. Which proto-oncogene family encodes small GTP-binding proteins and is frequently mutated in cancer?
  58. Answer: CARCINOMA
  59. G1
  60. G5
  61. What type of growth pattern is characteristic of many benign tumors?
  62. O4
  63. 🔥 Nomenclature Challenge
  64. A malignant neoplasm derived from mesenchymal tissue is called a:
  65. Which TNM component is represented by the lymph-node involvement?
  66. What process allows a growing tumor to develop its own blood supply?
  67. Answer: SARCOMA
  68. I1
  69. * Melanoma
  70. A benign epithelial tumor producing finger-like or wart-like projections is called a:
  71. N1
  72. I3
  73. A benign glandular epithelial neoplasm is called an:
  74. Answer: RB
  75. N3
  76. What structure must an epithelial carcinoma breach to become invasive?
  77. I4
  78. * Seminoma
  79. Answer: GRADE
  80. G2
  81. A tumor is well circumscribed, slow growing, and remains localized. What type of neoplasm is this?
  82. What major feature is absent in typical benign neoplasms?
  83. Answer: TERATOMA
  84. O2
  85. Which tumor suppressor gene regulates the G1/S cell-cycle checkpoint?
  86. Answer: ONCOGENE